Warning GHS02GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Isobutyl methacrylate

Also known as: 2-Propenoic acid, 2-methyl-, 2-methylpropyl ester, BRN 1747595, EINECS 202-613-0, Isobutyl alpha-methacrylate, Isobutyl alpha-methylacrylate (+7 more)

CAS 97-86-9

Isobutyl methacrylate (CAS 97-86-9) is a chemical substance with GHS signal word Warning; key hazard signal: H226; H335; H315; H317. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Isobutyl Methacrylate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
Isobutyl methacrylate
CAS Number
97-86-9
DTXSID
DTXSID3025461
Molecular Formula
C8H14O2
InChI Key
RUMACXVDVNRZJZ-UHFFFAOYSA-N
Monoisotopic Mass
142.09938
Synonyms
2-Propenoic acid, 2-methyl-, 2-methylpropyl esterBRN 1747595EINECS 202-613-0Isobutyl alpha-methacrylateIsobutyl alpha-methylacrylateIsobutyl 2-methyl-2-propenoate2-Methylpropyl methacrylate2-Methylpropyl 2-methyl-2-propenoateNSC 18607Propenoic acid, 2-methyl, isobutyl esterIsobutylester kyseliny methakryloveUNII-V11534UYZ0

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Skin Sens. 1BH226; H335; H315; H317GHS02; GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Film formerFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
=409mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=415.9mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
V11534UYZ0UNIIFDA UNII substance identifier--openFDA substances
V11534UYZ0UNIIFDA UNII substance identifier--openFDA substances
V11534UYZ0UNIIFDA UNII substance identifier--openFDA substances
V11534UYZ0UNIIFDA UNII substance identifier--openFDA substances
=9590mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredIsobutyl methacrylate202-613-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1453087
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the GHS hazard classification for Isobutyl methacrylate?

Isobutyl methacrylate (CAS 97-86-9) is classified under EU CLP Annex VI as Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Skin Sens. 1B with signal word Warning. Hazard statements: H226; H335; H315; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Isobutyl methacrylate?

Isobutyl methacrylate has 7 NOAEL studies in the database. The lowest reported value is 409 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Isobutyl methacrylate?

Isobutyl methacrylate appears on 2 regulatory/inventory lists including Europe, Indirect additives food contact (10/2018). Source: EPA CPDat.

Is Isobutyl methacrylate used in cosmetics?

Yes, Isobutyl methacrylate is also indexed as a cosmetic ingredient under the name Isobutyl Methacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Isobutyl methacrylate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Isobutyl methacrylate used outside industrial chemicals?

Isobutyl methacrylate also appears in cosmetics, pharmaceutical, cannabis databases.