What is the NOAEL for Ethyl lactate?
Ethyl lactate has 12 NOAEL studies in the database. The lowest reported value is 7.053 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethyl lactate
Also known as: Propanoic acid, 2-hydroxy-, ethyl ester, 4-03-00-00643, BRN 1209448, EINECS 202-598-0, Ethyl alpha-hydroxypropionate (+3 more)
CAS 97-64-3
Ethyl lactate (CAS 97-64-3) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Ethyl lactate is classified GHS Danger (H226, H318, H335, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
10
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Ethyl lactate
CAS Number
97-64-3
DTXSID
DTXSID6029127
Molecular Formula
C5H10O3
InChI Key
LZCLXQDLBQLTDK-UHFFFAOYSA-N
Monoisotopic Mass
118.062994
Synonyms
Propanoic acid, 2-hydroxy-, ethyl ester4-03-00-00643BRN 1209448EINECS 202-598-0Ethyl alpha-hydroxypropionateFEMA No. 2440Ethylester kyseliny mlecneUNII-F3P750VW8I
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
27 records
SolventFragranceFlavouring and nutrientPharmaceuticalCleaning agentDiluent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| fracking; water | NY Department of Conservation | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =7.053 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| F3P750VW8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F3P750VW8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F3P750VW8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F3P750VW8I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 5400 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =8200 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =72474 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
| <75 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~600 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ethyl lactate | 202-598-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3186323
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Ethyl lactate?
Ethyl lactate appears on 10 regulatory/inventory lists including active_ingredient; Australia, active_ingredient; animal_products; Europe; pharmaceutical; residue, IFRA Transparency, and 7 more. Source: EPA CPDat.
Is Ethyl lactate used in cosmetics?
Yes, Ethyl lactate is also indexed as a cosmetic ingredient under the name Ethyl Lactate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethyl lactate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Ethyl lactate have different safety status in cosmetics vs industrial chemicals?
Ethyl lactate is classified GHS Danger (H226, H318, H335, H319) in the chemicals database but is allowed in EU cosmetics.
Is Ethyl lactate used outside industrial chemicals?
Ethyl lactate also appears in cosmetics, pharmaceutical, cannabis databases.