What is the NOAEL for 1-Butanol, 2-amino-?
1-Butanol, 2-amino- has 10 NOAEL studies in the database. The lowest reported value is 1.4 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Butanol, 2-amino-
CAS 96-20-8
1-Butanol, 2-amino- (CAS 96-20-8) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
1-Butanol, 2-amino- is classified GHS Danger (H302, H314, H318, H400, H411, H361f) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
1-Butanol, 2-amino-
CAS Number
96-20-8
DTXSID
DTXSID60859935
Molecular Formula
C4H11NO
InChI Key
JCBPETKZIGVZRE-UHFFFAOYSA-N
Monoisotopic Mass
89.084064
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
pH regulating agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1.4 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| N008Q02GPS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N008Q02GPS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N008Q02GPS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N008Q02GPS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =800 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| >1000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1800 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2800 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =10 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-aminobutan-1-ol | 202-488-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL327032
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is 1-Butanol, 2-amino- used in cosmetics?
Yes, 1-Butanol, 2-amino- is also indexed as a cosmetic ingredient under the name 2-Aminobutanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Butanol, 2-amino- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 1-Butanol, 2-amino- have different safety status in cosmetics vs industrial chemicals?
1-Butanol, 2-amino- is classified GHS Danger (H302, H314, H318, H400, H411, H361f) in the chemicals database but is restricted in EU cosmetics.
Is 1-Butanol, 2-amino- used outside industrial chemicals?
1-Butanol, 2-amino- also appears in cosmetics, pharmaceutical databases.