What is the NOAEL for 1'-Acetonaphthone?
1'-Acetonaphthone has 11 NOAEL studies in the database. The lowest reported value is 0.822 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1'-Acetonaphthone
Also known as: 1-(Naphthalen-1-yl)ethanone, 1-(Naphthalen-1-yl)ethan-1-one, 1-(Naphthalen-4-yl)ethanone, alpha-Methyl naphthyl ketone, 4-07-00-01292 (+7 more)
CAS 941-98-0
1'-Acetonaphthone (CAS 941-98-0) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
1'-Acetonaphthone
CAS Number
941-98-0
DTXSID
DTXSID4052635
Molecular Formula
C12H10O
InChI Key
QQLIGMASAVJVON-UHFFFAOYSA-N
Monoisotopic Mass
170.073165
Synonyms
1-(Naphthalen-1-yl)ethanone1-(Naphthalen-1-yl)ethan-1-one1-(Naphthalen-4-yl)ethanonealpha-Methyl naphthyl ketone4-07-00-01292alpha-Acetonaphthonealpha-AcetylnaphthaleneBRN 1100618EINECS 213-384-1Methyl alpha-naphthyl ketonealpha-Naphthyl methyl ketoneUNII-U44R403XVS
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
DeodorizerFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| detected; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.822 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| U44R403XVS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U44R403XVS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U44R403XVS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U44R403XVS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =33 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =33 | mg/kg | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =33 | mg/kg | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1'-acetonaphthone | 213-384-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1'-Acetonaphthone?
1'-Acetonaphthone appears on 5 regulatory/inventory lists including IFRA Transparency, consumer_product, detected; Europe; Vehicle - car interior, and 2 more. Source: EPA CPDat.
Is 1'-Acetonaphthone used in cosmetics?
Yes, 1'-Acetonaphthone is also indexed as a cosmetic ingredient under the name 1-Acetonaphthone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1'-Acetonaphthone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1'-Acetonaphthone used outside industrial chemicals?
1'-Acetonaphthone also appears in cosmetics, cannabis databases.