What is the NOAEL for Propan-2-yl benzoate?
Propan-2-yl benzoate has 6 NOAEL studies in the database. The lowest reported value is 70.48 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Propan-2-yl benzoate
Also known as: Benzoic acid, 1-methylethyl ester, 4-09-00-00289, BRN 2044384, EINECS 213-361-6, FEMA No. 2932 (+3 more)
CAS 939-48-0
Propan-2-yl benzoate (CAS 939-48-0) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Propan-2-yl benzoate
CAS Number
939-48-0
DTXSID
DTXSID9044746
Molecular Formula
C10H12O2
InChI Key
FEXQDZTYJVXMOS-UHFFFAOYSA-N
Monoisotopic Mass
164.08373
Synonyms
Benzoic acid, 1-methylethyl ester4-09-00-00289BRN 2044384EINECS 213-361-6FEMA No. 29321-Methylethyl benzoateIsopropylester kyseliny benzooveUNII-1Q2618834N
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
PreservativeFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =70.48 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 1Q2618834N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q2618834N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q2618834N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q2618834N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3730 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Isopropyl benzoate | 213-361-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BENZOIC ACID 1-METHYLETHYL ESTER
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Propan-2-yl benzoate?
Propan-2-yl benzoate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Propan-2-yl benzoate used in cosmetics?
Yes, Propan-2-yl benzoate is also indexed as a cosmetic ingredient under the name Isopropyl Benzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Propan-2-yl benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Propan-2-yl benzoate used outside industrial chemicals?
Propan-2-yl benzoate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.