Also known as: gamma-Aminopropyltriethoxy silane, 1-Propanamine, 3-(triethoxysilyl)-, 4-04-00-04273, (gamma-Aminopropyl)triethoxysilane, BRN 1754988 (+7 more)
CAS 919-30-2
3-Aminopropyltriethoxysilane (CAS 919-30-2) is a chemical substance with GHS signal word Danger; key hazard signal: H302; H314. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Aminopropyl Triethoxysilane →
3-Aminopropyltriethoxysilane is classified GHS Danger (H302, H314) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Acute Tox. 4 *; Skin Corr. 1B | H302; H314 | GHS07; GHS05 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =14 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| L8S6UBW552 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L8S6UBW552 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L8S6UBW552 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L8S6UBW552 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| >0.0452 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >0.1448 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >7.35 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >1340 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| =1570 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| >1610 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| =1780 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| <1850 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| =2830 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| <4980 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| >=147000 | mg/m3 | LOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =600 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=75 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 24 of 24 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-aminopropyltriethoxysilane | 213-048-4 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →3-Aminopropyltriethoxysilane (CAS 919-30-2) is classified under EU CLP Annex VI as Acute Tox. 4 *; Skin Corr. 1B with signal word Danger. Hazard statements: H302; H314. Source: EU CLP Annex VI (ECHA).
3-Aminopropyltriethoxysilane has 24 NOAEL studies in the database. The lowest reported value is 14 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
3-Aminopropyltriethoxysilane appears on 2 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018). Source: EPA CPDat.
Yes, 3-Aminopropyltriethoxysilane is also indexed as a cosmetic ingredient under the name Aminopropyl Triethoxysilane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
3-Aminopropyltriethoxysilane is classified GHS Danger (H302, H314) in the chemicals database but is allowed in EU cosmetics.
3-Aminopropyltriethoxysilane also appears in cosmetics, pharmaceutical, cannabis databases.