What is the NOAEL for 2-Methylnaphthalene?
2-Methylnaphthalene has 18 NOAEL studies in the database. The lowest reported value is 0.003 mg/m3 via inhalation in Human. Source: ToxValDB_Pennsylvania_DEP_ToxValues.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Methylnaphthalene
Also known as: EINECS 202-078-3, beta-Methylnaphthalene, Naphthalene, beta-methyl-, UNII-S8MCX3C16H
CAS 91-57-6
2-Methylnaphthalene (CAS 91-57-6) is a chemical substance. Key regulatory status: REACH registered, 15 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
2-Methylnaphthalene is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H411, H319, H335, H336, H373, H401, H315).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
18
SOURCE
chemical inventory jurisdictions
Regulatory lists
15
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
2-Methylnaphthalene
CAS Number
91-57-6
DTXSID
DTXSID4020878
Molecular Formula
C11H10
InChI Key
QIMMUPPBPVKWKM-UHFFFAOYSA-N
Monoisotopic Mass
142.07825
Synonyms
EINECS 202-078-3beta-MethylnaphthaleneNaphthalene, beta-methyl-UNII-S8MCX3C16H
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes. |
| Long-term Effects | Repeated or prolonged inhalation may cause effects on the lungs. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
1 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| ACGIH | TWA | 0.5 ppm [2006] | 0.5 | - | Y |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
15 records
| List | Keyword | Source |
|---|---|---|
| Cleaning products and household care - air freshener; Europe | Danish Environmental Protection Agency | Danish EPA |
| Raw materials | Air Water INC | Air Water INC |
| detected; Toys and children's products | Springer | Published Articles |
| detected; Toys and children's products | Scientific Reports | Published Articles |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; ground_water; MN Chemical Screening | Minnesota Pollution Control Agency | State of Minnesota |
| IFRA Transparency | IFRA | IFRA |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =4.7 | mg/kg bw/day | BMD | oral | Mouse | ToxValDB_PPRTV_(CPHEA) |
| =4.7 | mg/kg/day | BMD 05 | oral | - | EPA_IRIS_iris_rfd_systems.csv |
| =3.5 | mg/kg bw/day | BMDL (05) | oral | Mouse | ToxValDB_Health_Canada |
| =4.3 | mg/kg bw/day | BMDL (05) | oral | Mouse | ToxValDB_ATSDR_MRLs |
| =4.7 | mg/kg bw/day | BMDL (05) | oral | Mouse | ToxValDB_IRIS |
| S8MCX3C16H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S8MCX3C16H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S8MCX3C16H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S8MCX3C16H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.04 | mg/kg bw/day | MRL | oral | Human | ToxValDB_ATSDR_MRLs |
| =0.003 | mg/m3 | RfC | inhalation | Human | ToxValDB_Pennsylvania_DEP_ToxValues |
| =0.014 | mg/m3 | RfC | inhalation | Human | ToxValDB_Alaska_DEC |
| =0.014 | mg/m3 | RfC | inhalation | Human | ToxValDB_Alaska_DEC |
| =0.0032 | mg/kg bw/day | RfD | dermal | Human | ToxValDB_Alaska_DEC |
| =0.0032 | mg/kg bw/day | RfD | dermal | Human | ToxValDB_Alaska_DEC |
| =0.004 | mg/kg bw/day | RfD | oral | Human | ToxValDB_Alaska_DEC |
| =0.004 | mg/kg bw/day | RfD | oral | Human | ToxValDB_Alaska_DEC |
| =0.004 | mg/kg/day | RfD | oral | - | EPA_IRIS_iris_rfd_systems.csv |
Showing 18 of 18 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-methylnaphthalene | 202-078-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
CHEMBL195895
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Methylnaphthalene?
2-Methylnaphthalene appears on 10 regulatory/inventory lists including Cleaning products and household care - air freshener; Europe, Raw materials, detected; Toys and children's products, and 7 more. Source: EPA CPDat.
What are the occupational exposure limits for 2-Methylnaphthalene?
Occupational exposure limits for 2-Methylnaphthalene are set by ACGIH. 1 limit value from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is 2-Methylnaphthalene used in cosmetics?
Yes, 2-Methylnaphthalene is also indexed as a cosmetic ingredient under the name 2-Methylnaphthalene. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Methylnaphthalene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Methylnaphthalene have different safety status in cosmetics vs industrial chemicals?
2-Methylnaphthalene is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H411, H319, H335, H336, H373, H401, H315).
Is 2-Methylnaphthalene used outside industrial chemicals?
2-Methylnaphthalene also appears in cosmetics, pharmaceutical, cannabis databases.