What is the NOAEL for Sodium alginate?
Sodium alginate has 12 NOAEL studies in the database. The lowest reported value is C269C4G2ZQ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sodium alginate
Also known as: Algiline, L'-Algiline, Algin (Laminaria spp. and other kelps), Algipon L-1168, Cohasal-IH (+8 more)
CAS 9005-38-3
Sodium alginate (CAS 9005-38-3) is a chemical substance. Key regulatory status: 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Sodium alginate
CAS Number
9005-38-3
DTXSID
DTXSID0040410
Synonyms
AlgilineL'-AlgilineAlgin (Laminaria spp. and other kelps)Algipon L-1168Cohasal-IHDuckalginFEMA No. 2014Manucol SS/LD2ManutexManutex RS-5Manutex rS1Sodium polymannuronate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
Viscosity modifierBinderFragranceFlavouring and nutrientThickening agentProcessing aids not otherwise specifiedEmulsifierSurfactant (surface active agent)Stabilizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - dental care - toothpaste | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| C269C4G2ZQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C269C4G2ZQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C269C4G2ZQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C269C4G2ZQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1.8 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 2000 | mg/kg bw/day | NOAEL | oral | guinea pig | COSMOS_DB |
| 2500 | mg/kg bw/day | NOAEL | oral | cat | COSMOS_DB |
| 5000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 7500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 11250 | mg/kg bw/day | NOAEL | oral | dog | COSMOS_DB |
| 37500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
Showing 12 of 12 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
thickener
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
188
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E401 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium alginate?
Sodium alginate appears on 8 regulatory/inventory lists including children; Europe; Personal care, children; Europe; Personal care - dental care - toothpaste, Europe; Personal care, and 5 more. Source: EPA CPDat.
Is Sodium alginate used in cosmetics?
Yes, Sodium alginate is also indexed as a cosmetic ingredient under the name Algin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium alginate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium alginate used outside industrial chemicals?
Sodium alginate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.