NOAEL Data Cosmetic Ingredient

Hydroxyethyl starch

Also known as: 2-Hydroxyethyl starch, Starch, 2-hydroxyethyl ether, O-(2-Hydroxyethyl)starch, 2-Hydroxyethyl starch ether, Hespander injection (+7 more)

CAS 9005-27-0

Hydroxyethyl starch (CAS 9005-27-0) is a chemical substance. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Arrowroot Powder →

SOURCE noael studies public
NOAEL studies
12
SOURCE chemical inventory jurisdictions
Regulatory lists
7
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 15 fields
Name
Hydroxyethyl starch
CAS Number
9005-27-0
DTXSID
DTXSID3046829
Synonyms
2-Hydroxyethyl starchStarch, 2-hydroxyethyl etherO-(2-Hydroxyethyl)starch2-Hydroxyethyl starch etherHespander injectionOnkohasHydroxyathylstarkeHidroxietil almidonUNII-875Y4127EAUNII-MOQ3RNM0SVUNII-1GVO236S58Tetrastarch

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 8 records
Binder

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 7 records
ListKeywordSource
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)
Canada; pharmaceuticalDrugBankDrugBank
pharmaceuticalFDAUnited States Food and Drug Administration (FDA)
Canada; pharmaceuticalDrugBankDrugBank
Canada; pharmaceuticalDrugBankDrugBank
inert_ingredient; non_food_use; PesticidesEPACPCat
Canada; consumer_product; Substances in Products - Canada (4/2014)Government of CanadaCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 12 of 12 studies
ValueUnitEndpointRouteSpeciesSource
1GVO236S58UNIIFDA UNII substance identifier--openFDA substances
1GVO236S58UNIIFDA UNII substance identifier--openFDA substances
1GVO236S58UNIIFDA UNII substance identifier--openFDA substances
1GVO236S58UNIIFDA UNII substance identifier--openFDA substances
875Y4127EAUNIIFDA UNII substance identifier--openFDA substances
875Y4127EAUNIIFDA UNII substance identifier--openFDA substances
875Y4127EAUNIIFDA UNII substance identifier--openFDA substances
875Y4127EAUNIIFDA UNII substance identifier--openFDA substances
MOQ3RNM0SVUNIIFDA UNII substance identifier--openFDA substances
MOQ3RNM0SVUNIIFDA UNII substance identifier--openFDA substances
MOQ3RNM0SVUNIIFDA UNII substance identifier--openFDA substances
MOQ3RNM0SVUNIIFDA UNII substance identifier--openFDA substances

Showing 12 of 12 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
thickener
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
24
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Hydroxyethyl starch?

Hydroxyethyl starch has 12 NOAEL studies in the database. The lowest reported value is 1GVO236S58 UNII. Source: openFDA substances.

What regulatory lists include Hydroxyethyl starch?

Hydroxyethyl starch appears on 5 regulatory/inventory lists including Indirect additives food contact (10/2018), Canada; pharmaceutical, pharmaceutical, and 2 more. Source: EPA CPDat.

Is Hydroxyethyl starch used in cosmetics?

Yes, Hydroxyethyl starch is also indexed as a cosmetic ingredient under the name Arrowroot Powder. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hydroxyethyl starch come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Hydroxyethyl starch used outside industrial chemicals?

Hydroxyethyl starch also appears in cosmetics, pharmaceutical databases.