What is the NOAEL for Cellulose?
Cellulose has 60 NOAEL studies in the database. The lowest reported value is 5XDI2TS1EZ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Cellulose
Also known as: Sigmacell, α-Cellulose, beta-Amylose, Arbocell B 600/30, EINECS 232-674-9 (+9 more)
CAS 9004-34-6
Cellulose (CAS 9004-34-6) is a chemical substance. Key regulatory status: 11 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, OSHA.
View cosmetic safety profile for Microcrystalline Cellulose →
SOURCE
noael studies public
NOAEL studies
60
SOURCE
chemical inventory jurisdictions
Regulatory lists
11
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Cellulose
CAS Number
9004-34-6
DTXSID
DTXSID3050492
Synonyms
Sigmacellα-Cellulosebeta-AmyloseArbocell B 600/30EINECS 232-674-9HydroxycelluloseSpartose OM-22Whatman CC-31alpha-CelluloseUNII-OP1R32D61UUNII-SMD1X3XO9MUNII-I355QGZ19A
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
3 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 15 mg/m³ (total dust), 5 mg/m³ (respirable fraction) | - | 15 | N |
| NIOSH | TWA | 10 mg/m³ (total dust), 5 mg/m³ (respirable fraction) | - | 10 | N |
| CAL/OSHA | TWA | 10 mg/m³ (total dust), 5 mg/m³ (respirable fraction) | - | 10 | N |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
AbrasiveAbsorbentEmulsifierViscosity modifierFillerStabilizing agentOpaciferAnti-caking agentBinderAnti-adhesive/cohesiveThickening agentSurfactant (surface active agent)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
11 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Cleaning products and household care; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe | Danish EPA | Danish EPA |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| inert_ingredient; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 60 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5XDI2TS1EZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5XDI2TS1EZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5XDI2TS1EZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5XDI2TS1EZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7T9FYH5QMK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7T9FYH5QMK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7T9FYH5QMK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7T9FYH5QMK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 91B875MM4H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 91B875MM4H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 91B875MM4H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 91B875MM4H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C8DF2GF8L2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C8DF2GF8L2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C8DF2GF8L2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C8DF2GF8L2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HHJ82DN6MJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HHJ82DN6MJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HHJ82DN6MJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HHJ82DN6MJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KO5GYV0DCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KO5GYV0DCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KO5GYV0DCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KO5GYV0DCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L5EC3P45R8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L5EC3P45R8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L5EC3P45R8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L5EC3P45R8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OP1R32D61U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OP1R32D61U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OP1R32D61U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OP1R32D61U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PNR0YF693Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SMD1X3XO9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SMD1X3XO9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SMD1X3XO9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SMD1X3XO9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VG6UJI79NF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VG6UJI79NF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VG6UJI79NF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VG6UJI79NF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W7YXH6D4BD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W7YXH6D4BD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| X7XJ6RM9Q2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| X7XJ6RM9Q2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| X7XJ6RM9Q2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| X7XJ6RM9Q2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
Showing 50 of 60 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
1
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E460i — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Cellulose?
Cellulose appears on 10 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, Indirect additives food contact (10/2018), and 7 more. Source: EPA CPDat.
What are the occupational exposure limits for Cellulose?
Occupational exposure limits for Cellulose are set by OSHA, NIOSH, CAL/OSHA. 3 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Cellulose used in cosmetics?
Yes, Cellulose is also indexed as a cosmetic ingredient under the name Microcrystalline Cellulose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cellulose come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Cellulose used outside industrial chemicals?
Cellulose also appears in cosmetics, pharmaceutical, food safety, cannabis databases.