What is the NOAEL for Polyvinyl alcohol?
Polyvinyl alcohol has 57 NOAEL studies in the database. The lowest reported value is 50 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
IARC Group 3
Cosmetic Ingredient
Polyvinyl alcohol
Also known as: Ethenol, homopolymer, Alcotex 88/05, Alcotex 88/10, Alkotex, Galvatol 1-60 (+15 more)
CAS 9002-89-5
Polyvinyl alcohol (CAS 9002-89-5) is a chemical substance; key hazard signal: IARC Group 3. Key regulatory status: 14 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
57
SOURCE
chemical inventory jurisdictions
Regulatory lists
14
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Polyvinyl alcohol
CAS Number
9002-89-5
DTXSID
DTXSID4031930
Synonyms
Ethenol, homopolymerAlcotex 88/05Alcotex 88/10AlkotexGalvatol 1-60Gelvatol 2090Gohsenol GH 20Gohsenol GL 05Gohsenol GM 14Gohsenol GM 14LGohsenol KH 17Gohsenol NK 114
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 19, Sup 7 |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | May cause mechanical irritation. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Film formerViscosity modifierSealant (barrier)BinderThickening agentEmulsifierAdhesion/cohesion promoter
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
14 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bath salts | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts adhesive; Europe | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe | Danish EPA | Danish EPA |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
| Cleaning products and household care; Europe | Danish EPA | Danish EPA |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| Europe; Specialty occupational products | Danish Environmental Protection Agency | Danish EPA |
| Food contact items | Washington State Department of Ecology | State of Washington |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 57 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=50 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =50 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v52je09 |
| =50 | mg/kg bw/day | ADI | - | Rat | INCHEM_WHO_jecfa_jecmono_v52je09 |
| 1E30GE2EF7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1E30GE2EF7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1E30GE2EF7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1E30GE2EF7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2AVG41YG39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2AVG41YG39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2AVG41YG39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2AVG41YG39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 532B59J990 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 532B59J990 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 532B59J990 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 532B59J990 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 660SZ0AKDA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 660SZ0AKDA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 660SZ0AKDA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 660SZ0AKDA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8K8B5SD7ZR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8K8B5SD7ZR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8K8B5SD7ZR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8K8B5SD7ZR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 949E52Z6MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 949E52Z6MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 949E52Z6MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 949E52Z6MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BRY146A46V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BRY146A46V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BRY146A46V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BRY146A46V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C1MS7RRZ6L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C1MS7RRZ6L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C1MS7RRZ6L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C1MS7RRZ6L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5O20161WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5O20161WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5O20161WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I5O20161WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J1DZU42714 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J1DZU42714 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J1DZU42714 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J1DZU42714 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QP3MK8Z0XS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QP3MK8Z0XS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QP3MK8Z0XS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QP3MK8Z0XS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| >20000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 50 of 57 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
polymer
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
polyvinyl alcohol
ChEMBL Phase
Not listed
Adverse Events
47
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E1203 — ADI: 50 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Polyvinyl alcohol?
Polyvinyl alcohol appears on 14 regulatory/inventory lists including inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, children; Europe; Personal care, and 11 more. Source: EPA CPDat.
Is Polyvinyl alcohol a carcinogen according to IARC?
Polyvinyl alcohol is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is Polyvinyl alcohol used in cosmetics?
Yes, Polyvinyl alcohol is also indexed as a cosmetic ingredient under the name Polyvinyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polyvinyl alcohol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Polyvinyl alcohol used outside industrial chemicals?
Polyvinyl alcohol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.