What is the NOAEL for Polytetrafluoroethylene?
Polytetrafluoroethylene has 8 NOAEL studies in the database. The lowest reported value is E1NC1JVS3O UNII. Source: openFDA substances.
NOAEL Data
IARC Group 3
Cosmetic Ingredient
Polytetrafluoroethylene
Also known as: Algloflon, Algoflon, Fluon, Teflon, Tetran), Alkathene rxdg33, Balfon 7000, Ftorlon F-4MB (+14 more)
CAS 9002-84-0
Polytetrafluoroethylene (CAS 9002-84-0) is a chemical substance; key hazard signal: IARC Group 3. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC.
View cosmetic safety profile for PTFE (Polytetrafluoroethylene) →
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Polytetrafluoroethylene
CAS Number
9002-84-0
DTXSID
DTXSID7047724
Synonyms
AlgloflonAlgoflon, Fluon, Teflon, Tetran)Alkathene rxdg33Balfon 7000Ftorlon F-4MBFtoroplast F-4Ftoroplast F 4MBPolifenPolyflon D1Polyflon M12Polyflon M12APolyflon M21
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 19, Sup 7 |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FillerProcessing aids not otherwise specifiedLubricating agentViscosity modifierCorrosion inhibitorAnti-adhesive/cohesiveSurface modifierHardenerWaterproofing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Europe; Personal care - make-up and related | Danish EPA | Danish EPA |
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - make-up and related | Danish EPA | Danish EPA |
| Europe; Personal care - general moisturizing - hand/body lotion; Personal care - make-up and related; Personal care - shaving and hair removal - shaving cream; Personal care - sunscreen | Danish EPA | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| E1NC1JVS3O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1NC1JVS3O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1NC1JVS3O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E1NC1JVS3O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| 5 | % | LOAEL | oral | rat | COSMOS_DB |
| 1 | % | NOAEL | oral | rat | COSMOS_DB |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Frequently Asked Questions
What regulatory lists include Polytetrafluoroethylene?
Polytetrafluoroethylene appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, consumer_product; Europe, Indirect additives food contact (10/2018), and 2 more. Source: EPA CPDat.
Is Polytetrafluoroethylene a carcinogen according to IARC?
Polytetrafluoroethylene is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is Polytetrafluoroethylene used in cosmetics?
Yes, Polytetrafluoroethylene is also indexed as a cosmetic ingredient under the name PTFE (Polytetrafluoroethylene). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polytetrafluoroethylene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Polytetrafluoroethylene used outside industrial chemicals?
Polytetrafluoroethylene also appears in cosmetics databases.