What is the NOAEL for 2-tert-Butylcyclohexyl acetate?
2-tert-Butylcyclohexyl acetate has 9 NOAEL studies in the database. The lowest reported value is 364FV60913 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-tert-Butylcyclohexyl acetate
Also known as: Cyclohexanol, 2-(1,1-dimethylethyl)-, acetate, Cyclohexanol, 2-(1,1-dimethylethyl)-, 1-acetate, 2-t-Butylcyclohexyl acetate, 1-Acetoxy-2-tert-butylcyclohexane, 2-tert-Butylcyclohexanol acetate (+4 more)
CAS 88-41-5
2-tert-Butylcyclohexyl acetate (CAS 88-41-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 2-T-Butylcyclohexyl Acetate →
Cross-Vertical Regulatory Divergence
2-tert-Butylcyclohexyl acetate is classified GHS CMR hazard (H336, H351, H373, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
2-tert-Butylcyclohexyl acetate
CAS Number
88-41-5
DTXSID
DTXSID3036105
Molecular Formula
C12H22O2
InChI Key
FINOAUDUYKVGDS-UHFFFAOYSA-N
Monoisotopic Mass
198.16198
Synonyms
Cyclohexanol, 2-(1,1-dimethylethyl)-, acetateCyclohexanol, 2-(1,1-dimethylethyl)-, 1-acetate2-t-Butylcyclohexyl acetate1-Acetoxy-2-tert-butylcyclohexane2-tert-Butylcyclohexanol acetateo-t-Butylcyclohexyl acetate2-(1,1-Dimethylethyl)cyclohexanol acetateEINECS 201-828-7UNII-364FV60913
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceDeodorizerSolvent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 364FV60913 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 364FV60913 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 364FV60913 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 364FV60913 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| <50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_HESS |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 2-tert-Butylcyclohexyl acetate?
2-tert-Butylcyclohexyl acetate appears on 2 regulatory/inventory lists including IFRA Transparency, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is 2-tert-Butylcyclohexyl acetate used in cosmetics?
Yes, 2-tert-Butylcyclohexyl acetate is also indexed as a cosmetic ingredient under the name 2-T-Butylcyclohexyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-tert-Butylcyclohexyl acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-tert-Butylcyclohexyl acetate have different safety status in cosmetics vs industrial chemicals?
2-tert-Butylcyclohexyl acetate is classified GHS CMR hazard (H336, H351, H373, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
Is 2-tert-Butylcyclohexyl acetate used outside industrial chemicals?
2-tert-Butylcyclohexyl acetate also appears in cosmetics databases.