NOAEL Data Cosmetic Ingredient

Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate

CAS 872182-46-2

Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate (CAS 872182-46-2) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate →

SOURCE NOAEL studies
NOAEL studies
4
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate
CAS Number
872182-46-2
DTXSID
DTXSID401007429
Molecular Formula
C28H46O7
InChI Key
QHQPFWCUOFWVKE-UHFFFAOYSA-N
Monoisotopic Mass
494.324354

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
AntioxidantHumectantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
7D4Q5YJ8NVUNIIFDA UNII substance identifier--openFDA substances
7D4Q5YJ8NVUNIIFDA UNII substance identifier--openFDA substances
7D4Q5YJ8NVUNIIFDA UNII substance identifier--openFDA substances
7D4Q5YJ8NVUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the concentration in cosmetic products is intended to exceed 4% 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
4%
Category
Other
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate?

Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate has 4 NOAEL studies in the database. The lowest reported value is 7D4Q5YJ8NV UNII. Source: openFDA substances.

Is Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate used in cosmetics?

Yes, Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate is also indexed as a cosmetic ingredient under the name Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate used outside industrial chemicals?

Bis(2-ethylhexyl) [(4-hydroxy-3,5-dimethoxyphenyl)methyl]propanedioate also appears in cosmetics databases.