NOAEL Data REACH Registered Cosmetic Ingredient

HC Yellow no. 9

Also known as: UNII-91P0Z9H61V, 1,2-Ethanediamine, N-(5-methoxy-2-nitrophenyl)-, monohydrochloride, 1,2-Ethanediamine, n1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1), Ethylenediamine, N-(5-methoxy-2-nitrophenyl)-, hydrochloride, HC Yellow 9 (+1 more)

CAS 86419-69-4

HC Yellow no. 9 (CAS 86419-69-4) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for HC Yellow No. 9 →

SOURCE noael studies public
NOAEL studies
42
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
HC Yellow no. 9
CAS Number
86419-69-4
DTXSID
DTXSID40235536
Molecular Formula
C9H13N3O3.ClH
InChI Key
AFAJYBYVKUTWJK-UHFFFAOYSA-N
Monoisotopic Mass
247.072369
Synonyms
UNII-91P0Z9H61V1,2-Ethanediamine, N-(5-methoxy-2-nitrophenyl)-, monohydrochloride1,2-Ethanediamine, n1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1)Ethylenediamine, N-(5-methoxy-2-nitrophenyl)-, hydrochlorideHC Yellow 9Imexine FAD

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
Europe; Personal care; restrictedEuropean CommissionCosIng
Canada; Personal care; Substances in PCP - Canada (4/2014)Government of CanadaCPCat
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 42 of 42 studies
ValueUnitEndpointRouteSpeciesSource
250mg/kg bw/day--ratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
91P0Z9H61VUNIIFDA UNII substance identifier--openFDA substances
91P0Z9H61VUNIIFDA UNII substance identifier--openFDA substances
91P0Z9H61VUNIIFDA UNII substance identifier--openFDA substances
91P0Z9H61VUNIIFDA UNII substance identifier--openFDA substances
=0.09mg/kg bwNOAELdermalratSCCS_vision_codex
=0.09mg/kg bwNOAELdermalratSCCS_vision_codex
=0.09mg/kg bwNOAELdermalratSCCS_vision_codex
=0.09mg/kg bwNOAELdermalratSCCS_vision_codex
=70mg/kg bw/dayNOAELoralmouseSCCS_vision_codex
=70mg/kg bw/dNOAELdermalratSCCS_vision_codex
=70mg/kg bw/dayNOAELoralmouseSCCS_vision_codex
=70mg/kg bw/dNOAELdermalratSCCS_vision_codex
=70mg/kg bw/dayNOAELoralmouseSCCS_vision_codex
=70mg/kg bw/dNOAELdermalratSCCS_vision_codex
=70mg/kg bw/dayNOAELoralmouseSCCS_vision_codex
=70mg/kg bw/dNOAELdermalratSCCS_vision_codex
=80mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=80mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=80mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=80mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=100mg/kg bw/dayNOAELoralratSCCS_vision_codex
=100mg/kg bw/dayNOAELoralratSCCS_vision_codex
=100mg/kg bw/dayNOAELoralratSCCS_vision_codex
=100mg/kg bw/dayNOAELoralratSCCS_vision_codex
=250mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=250mg/kg bw/dNOAELoralratSCCS_vision_codex
=250mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=250mg/kg bw/dNOAELoralratSCCS_vision_codex
=250mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=250mg/kg bw/dNOAELoralratSCCS_vision_codex
=250mg/kg bw/dayNOAEL-ratSCCS_vision_codex
=250mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.09mg/kg bwdermal absorptiondermalratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=70mg/kg bw/ddermal absorptiondermalratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
=70mg/kg bw/ddermal absorptiondermalratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
70mg/kg bw/daydevelopmental toxicityoralmouseUnifiedCodex:SCCS_SHADOW:beta.noael_studies
80mg/kg bw/daygenotoxicity-ratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
250mg/kg bw/daygenotoxicity--UnifiedCodex:SCCS_SHADOW:beta.noael_studies
100mg/kg bw/dayrepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
250mg/kg bw/drepeated dose toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies
70mg/kg bw/dreproductive toxicityoralratUnifiedCodex:SCCS_SHADOW:beta.noael_studies

Showing 42 of 42 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered1,2-Ethanediamine, N-(5-methoxy-2-nitrophenyl)-, monohydrochloride415-480-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
0.5%
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for HC Yellow no. 9?

HC Yellow no. 9 has 42 NOAEL studies in the database. The lowest reported value is 250 mg/kg bw/day in rat. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.

What regulatory lists include HC Yellow no. 9?

HC Yellow no. 9 appears on 3 regulatory/inventory lists including Europe; Personal care; restricted, Canada; Personal care; Substances in PCP - Canada (4/2014), children; Europe; Personal care. Source: EPA CPDat.

Is HC Yellow no. 9 used in cosmetics?

Yes, HC Yellow no. 9 is also indexed as a cosmetic ingredient under the name HC Yellow No. 9. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for HC Yellow no. 9 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does HC Yellow no. 9 have different safety status in cosmetics vs industrial chemicals?

HC Yellow no. 9 is classified GHS Danger (H302, H301) in the chemicals database but is restricted in EU cosmetics at max 0.5%.

Is HC Yellow no. 9 used outside industrial chemicals?

HC Yellow no. 9 also appears in cosmetics databases.