What is the NOAEL for Black cohosh?
Black cohosh has 4 NOAEL studies in the database. The lowest reported value is K73E24S6X9 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Black cohosh
Also known as: Cimicfuga racemosa extract, Cimicifuga racemosa, EINECS 283-951-6, Bugbane, black, Actaea racemosa (+2 more)
CAS 84776-26-1
Black cohosh (CAS 84776-26-1) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Black Cohosh Root Extract →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Black cohosh
CAS Number
84776-26-1
DTXSID
DTXSID2030857
Synonyms
Cimicfuga racemosa extractCimicifuga racemosaEINECS 283-951-6Bugbane, blackActaea racemosaCohosh, BlackRemifemin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
HumectantSoftener and conditionerBiocideAntioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| K73E24S6X9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K73E24S6X9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K73E24S6X9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K73E24S6X9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Plant Extract
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
138
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Black cohosh?
Black cohosh appears on 2 regulatory/inventory lists including Canada; pharmaceutical, Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Black cohosh used in cosmetics?
Yes, Black cohosh is also indexed as a cosmetic ingredient under the name Black Cohosh Root Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Black cohosh come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Black cohosh used outside industrial chemicals?
Black cohosh also appears in cosmetics, pharmaceutical databases.