What is the NOAEL for Theobroma cacao extract?
Theobroma cacao extract has 3 NOAEL studies in the database. The lowest reported value is 2140 mg/kg bw/day via oral in rat. Source: COSMOS_DB.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Theobroma cacao extract
Also known as: EINECS 283-480-6, Cocoa extract, Cacao Bean Extract, Cocoa or Cocoa Butter
CAS 84649-99-0
Theobroma cacao extract (CAS 84649-99-0) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Theobroma Cacao Seed Extract →
SOURCE
noael studies public
NOAEL studies
3
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
7 fields
Name
Theobroma cacao extract
CAS Number
84649-99-0
DTXSID
DTXSID301018356
Synonyms
EINECS 283-480-6Cocoa extractCacao Bean ExtractCocoa or Cocoa Butter
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
HumectantAbrasiveAntioxidantDeodorizerSoftener and conditionerFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| ~10000 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 2140 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 4280 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 3 of 3 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Cocoa, ext. | 283-480-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Theobroma cacao extract?
Theobroma cacao extract appears on 4 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, Europe; Personal care, and 1 more. Source: EPA CPDat.
Is Theobroma cacao extract used in cosmetics?
Yes, Theobroma cacao extract is also indexed as a cosmetic ingredient under the name Theobroma Cacao Seed Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Theobroma cacao extract come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Theobroma cacao extract used outside industrial chemicals?
Theobroma cacao extract also appears in cosmetics, food safety databases.