NOAEL Data REACH Registered Cosmetic Ingredient

5-Amino-6-chloro-o-cresol

Also known as: EINECS 283-144-9, UNII-8077WHL3XK

CAS 84540-50-1

5-Amino-6-chloro-o-cresol (CAS 84540-50-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for 5-Amino-6-Chloro-o-Cresol →

SOURCE NOAEL studies
NOAEL studies
40
SOURCE Chemical inventory jurisdictions
Regulatory lists
3
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
5-Amino-6-chloro-o-cresol
CAS Number
84540-50-1
DTXSID
DTXSID80233531
Molecular Formula
C7H8ClNO
InChI Key
XYRDGCCCBJITBH-UHFFFAOYSA-N
Monoisotopic Mass
157.029442
Synonyms
EINECS 283-144-9UNII-8077WHL3XK

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
BiocideDye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 40 of 40 studies
ValueUnitEndpointRouteSpeciesSource
100mg/kg/day---Regulatory source
8077WHL3XKUNIIFDA UNII substance identifier--openFDA substances
8077WHL3XKUNIIFDA UNII substance identifier--openFDA substances
8077WHL3XKUNIIFDA UNII substance identifier--openFDA substances
8077WHL3XKUNIIFDA UNII substance identifier--openFDA substances
100mg/kg bw/dayLOAELoralratCOSMOS DB
=24mg/kg bw/dNOAEL-ratSCCS Opinion
=24mg/kg bw/dNOAEL-ratSCCS Opinion
=24mg/kg bw/dNOAEL-ratSCCS Opinion
=24mg/kg bw/dNOAEL-ratSCCS Opinion
=30mg/kg bw/dNOAEL-ratSCCS Opinion
=30mg/kg bw/dNOAEL-ratSCCS Opinion
=30mg/kg bw/dNOAEL-ratSCCS Opinion
=30mg/kg bw/dNOAEL-ratSCCS Opinion
=33mg/kg bw/dayNOAELdermalrabbitSCCS Opinion
=33mg/kg bw/dayNOAELdermalrabbitSCCS Opinion
=33mg/kg bw/dayNOAELdermalrabbitSCCS Opinion
=33mg/kg bw/dayNOAELdermalrabbitSCCS Opinion
=90mg/kg/dNOAEL-ratSCCS Opinion
=90mg/kg/dNOAEL-ratSCCS Opinion
=90mg/kg/dNOAEL-ratSCCS Opinion
=90mg/kg/dNOAEL-ratSCCS Opinion
=100mg/kg bw/dayNOAELoralRatECHA
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=100mg/kg/dayNOAEL--SCCS Opinion
=270mg/kg bw/dNOAEL-ratSCCS Opinion
=270mg/kg bw/dNOAEL-ratSCCS Opinion
=270mg/kg bw/dNOAEL-ratSCCS Opinion
=270mg/kg bw/dNOAEL-ratSCCS Opinion
<750mg/kg bw/dayNOAELoralRatECHA
=90mg/kg bw/dayNOELoralRatECHA
=270mg/kg bw/dayNOELoralRatECHA
33mg/kg bw/daydermal absorptiondermalrabbitRegulatory source
24mg/kg bw/ddevelopmental toxicity-ratRegulatory source
90mg/kg/ddevelopmental toxicity-ratRegulatory source
90mg/kg/ddevelopmental toxicity-ratRegulatory source
270mg/kg bw/ddevelopmental toxicity-ratRegulatory source
30mg/kg bw/dirritation-ratRegulatory source

Showing 40 of 40 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
Registered3-amino-2-chlor-6-methylphenol283-144-9ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 5-Amino-6-chloro-o-cresol?

5-Amino-6-chloro-o-cresol has 40 NOAEL studies in the database. The lowest reported value is 100 mg/kg/day. Source: Regulatory source.

What regulatory lists include 5-Amino-6-chloro-o-cresol?

5-Amino-6-chloro-o-cresol appears on 1 regulatory/inventory list including Europe; Personal care - hair coloring. Source: EPA CPDat.

Is 5-Amino-6-chloro-o-cresol used in cosmetics?

Yes, 5-Amino-6-chloro-o-cresol is also indexed as a cosmetic ingredient under the name 5-Amino-6-Chloro-o-Cresol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 5-Amino-6-chloro-o-cresol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 5-Amino-6-chloro-o-cresol used outside industrial chemicals?

5-Amino-6-chloro-o-cresol also appears in cosmetics databases.