NOAEL Data REACH Registered Cosmetic Ingredient

Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate

Also known as: Phosphinic acid, P-phenyl-P-(2,4,6-trimethylbenzoyl)-, ethyl ester, Ethyl (mesitylcarbonyl)phenylphosphinate

CAS 84434-11-7

Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate (CAS 84434-11-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L) →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate

CAS Number

84434-11-7

DTXSID

DTXSID40868808

Molecular Formula

C18H21O3P

InChI Key

ZMDDERVSCYEKPQ-UHFFFAOYSA-N

Monoisotopic Mass

316.122832

Synonyms

Phosphinic acid, P-phenyl-P-(2,4,6-trimethylbenzoyl)-, ethyl esterEthyl (mesitylcarbonyl)phenylphosphinate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records

Photosensitizers

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies

Value	Unit	Endpoint	Route	Species	Source
=4.93	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
71TY9W41AJ	UNII	FDA UNII substance identifier	-	-	openFDA substances
71TY9W41AJ	UNII	FDA UNII substance identifier	-	-	openFDA substances
71TY9W41AJ	UNII	FDA UNII substance identifier	-	-	openFDA substances
71TY9W41AJ	UNII	FDA UNII substance identifier	-	-	openFDA substances
=300	mg/kg bw/day	LEL	oral	Rat	ToxValDB_EPA_TSCA_8e

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate	282-810-6	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed_with_terms

Conditions

Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate?

Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate has 6 NOAEL studies in the database. The lowest reported value is 4.93 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate used in cosmetics?

Yes, Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate is also indexed as a cosmetic ingredient under the name Ethyl Trimethylbenzoyl Phenylphosphinate (TPO-L). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate used outside industrial chemicals?

Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate also appears in cosmetics databases.