Also known as: C.I Solvent yellow 14 (1-Phenylazo-2-naphthol), 2-Naphthalenol, 1-(phenyldiazenyl)-, 2-Naphthalenol, 1-(phenylazo)-, 1-(Phenyldiazenyl)naphthalen-2-ol, 2-Naphthalenol, 1-(2-phenyldiazenyl)- (+15 more)
CAS 842-07-9
C.I. Solvent Yellow 14 (CAS 842-07-9) is a chemical substance with GHS signal word Warning; key hazard signal: H351; H341; H317; H413. Key regulatory status: California Proposition 65, REACH registered, 12 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, IARC, ECHA REACH, CA Prop 65, EPA TRI.
View cosmetic safety profile for CI 12010 (Sudan I / Solvent Yellow 14) →
C.I. Solvent Yellow 14 is prohibited in EU cosmetics but has active industrial GHS classifications (H351, H341, H317, H413).
CAS, identifiers, formula, and alternate names for the matched substance record.
Carcinogenic hazard classification from IARC monograph evaluations.
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 8, Sup 7 |
California OEHHA listing status and toxicity category.
| Chemical | Toxicity Type | Cancer | Developmental | Listed |
|---|---|---|---|---|
| - | cancer | Yes | No | - |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Carc. 2; Muta. 2; Skin Sens. 1; Aquatic Chronic 4 | H351; H341; H317; H413 | GHS08; GHS07 | Warning |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| OEHHA Proposition 65 (3/2019) | STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY | OEHHA Proposition 65 List |
| children; WA Children's Safe Product Act (4/2020) | State of Washington Department of Ecology | State of Washington |
| children | Vermont Department of Health | State of Vermont |
| OEHHA Proposition 65 (1/2023) | California Office of Environmental Health Hazard Assessment | OEHHA Proposition 65 List |
| children | Oregon Health Authority | State of Oregon |
| banned; Europe; Personal care | European Commission | CosIng |
| OEHHA Proposition 65 (3/2019) | STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY | OEHHA Proposition 65 List |
| children; WA Children's Safe Product Act (4/2020) | State of Washington Department of Ecology | State of Washington |
| children | Vermont Department of Health | State of Vermont |
| OEHHA Proposition 65 (1/2023) | California Office of Environmental Health Hazard Assessment | OEHHA Proposition 65 List |
| children | Oregon Health Authority | State of Oregon |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5.43065296898055 | uM | AC50 | - | - | NTP_ICE_endocrine |
| 3.16033910455903 | uM | ACC | - | - | NTP_ICE_endocrine |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| - | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| =11.2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 48I7IBB68J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 48I7IBB68J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 48I7IBB68J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 48I7IBB68J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.00277 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =12.5 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ToxRefDB |
| =12.5 | mg/kg bw/day | LEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =25 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ToxRefDB |
| =25 | mg/kg bw/day | LEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =75 | mg/kg bw/day | LEL | oral | Mouse | ToxValDB_ToxRefDB |
| =75 | mg/kg bw/day | LEL | oral | mouse (b6c3f1; B6C3F1) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =150 | mg/kg bw/day | LEL | oral | Mouse | ToxValDB_ToxRefDB |
| =150 | mg/kg bw/day | LEL | oral | mouse (b6c3f1; B6C3F1) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =25 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ToxRefDB |
| =25 | mg/kg bw/day | LOAEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =50 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ToxRefDB |
| =50 | mg/kg bw/day | LOAEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =150 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ToxRefDB |
| =150 | mg/kg bw/day | LOAEL | oral | mouse (b6c3f1; B6C3F1) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =300 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ToxRefDB |
| =300 | mg/kg bw/day | LOAEL | oral | mouse (b6c3f1; B6C3F1) | ToxRefDB_ToxRefDB_v3_pod.csv |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 0.117 | unitless | Model Score | - | - | NTP_ICE_endocrine |
| >- | mg/kg bw/day | NEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =12.5 | mg/kg bw/day | NEL | oral | Rat | ToxValDB_ToxRefDB |
| =12.5 | mg/kg bw/day | NEL | oral | rat (fischer; Fischer 344) | ToxRefDB_ToxRefDB_v3_pod.csv |
| =75 | mg/kg bw/day | NEL | oral | Mouse | ToxValDB_ToxRefDB |
| =75 | mg/kg bw/day | NEL | oral | mouse (b6c3f1; B6C3F1) | ToxRefDB_ToxRefDB_v3_pod.csv |
| 500 | ppm | Top dose | Dosed feed | Rat | NTP_ICE_cancer |
| 1000 | ppm | Top dose | Dosed feed | Mouse | NTP_ICE_cancer |
Showing 39 of 39 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-phenylazo-2-naphthol | 212-668-2 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| C.I. Solvent Yellow 14 | - | - |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →C.I. Solvent Yellow 14 (CAS 842-07-9) is classified under EU CLP Annex VI as Carc. 2; Muta. 2; Skin Sens. 1; Aquatic Chronic 4 with signal word Warning. Hazard statements: H351; H341; H317; H413. Source: EU CLP Annex VI (ECHA).
C.I. Solvent Yellow 14 has 39 NOAEL studies in the database. The lowest reported value is 3.16033910455903 uM. Source: NTP_ICE_endocrine.
C.I. Solvent Yellow 14 appears on 6 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, OEHHA Proposition 65 (3/2019), children; WA Children's Safe Product Act (4/2020), and 3 more. Source: EPA CPDat.
C.I. Solvent Yellow 14 is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Yes, C.I. Solvent Yellow 14 is listed under California Proposition 65 for cancer. Source: California OEHHA Proposition 65.
Yes, C.I. Solvent Yellow 14 is also indexed as a cosmetic ingredient under the name CI 12010 (Sudan I / Solvent Yellow 14). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ECHA REACH, California Proposition 65, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
C.I. Solvent Yellow 14 is prohibited in EU cosmetics but has active industrial GHS classifications (H351, H341, H317, H413).
C.I. Solvent Yellow 14 also appears in cosmetics, pharmaceutical, cannabis databases.