What is the NOAEL for Ruscus aculeatus, extract?
Ruscus aculeatus, extract has 4 NOAEL studies in the database. The lowest reported value is ZW12V95I1Q UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ruscus aculeatus, extract
Also known as: Butcherbroom extract, Rusco extract, EINECS 281-682-9
CAS 84012-38-4
Ruscus aculeatus, extract (CAS 84012-38-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Ruscus Aculeatus Root Extract →
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Ruscus aculeatus, extract
CAS Number
84012-38-4
DTXSID
DTXSID301036483
Synonyms
Butcherbroom extractRusco extractEINECS 281-682-9
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
18 records
AstringentHumectantSoftener and conditionerStabilizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| ZW12V95I1Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZW12V95I1Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZW12V95I1Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ZW12V95I1Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ruscus aculeatus, ext. | 281-682-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
ChEMBL Phase
Not listed
Adverse Events
22
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Ruscus aculeatus, extract?
Ruscus aculeatus, extract appears on 1 regulatory/inventory list including Europe; Personal care. Source: EPA CPDat.
Is Ruscus aculeatus, extract used in cosmetics?
Yes, Ruscus aculeatus, extract is also indexed as a cosmetic ingredient under the name Ruscus Aculeatus Root Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ruscus aculeatus, extract come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Ruscus aculeatus, extract used outside industrial chemicals?
Ruscus aculeatus, extract also appears in cosmetics, pharmaceutical databases.