NOAEL Data REACH Registered Cosmetic Ingredient

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1)

Also known as: 2-[(3-amino-4-methoxyphenyl)amino]ethanol sulfate

CAS 83763-48-8

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) (CAS 83763-48-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 2-Amino-4-Hydroxyethylaminoanisole Sulfate →

SOURCE noael studies public
NOAEL studies
9
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1)
CAS Number
83763-48-8
DTXSID
DTXSID30892455
Molecular Formula
C9H14N2O2.H2O4S
InChI Key
GWHLYFOWAINYAH-UHFFFAOYSA-N
Monoisotopic Mass
280.072907
Synonyms
2-[(3-amino-4-methoxyphenyl)amino]ethanol sulfate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
Canada; Personal care; Substances in PCP - Canada (4/2014)Government of CanadaCPCat
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 9 of 9 studies
ValueUnitEndpointRouteSpeciesSource
UM91A54Z8GUNIIFDA UNII substance identifier--openFDA substances
UM91A54Z8GUNIIFDA UNII substance identifier--openFDA substances
UM91A54Z8GUNIIFDA UNII substance identifier--openFDA substances
UM91A54Z8GUNIIFDA UNII substance identifier--openFDA substances
15mg/kg bw/dayLOAELoralratCOSMOS_DB
=15mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=30mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>150mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=300mg/kg bw/dayNOAELdermalGuinea PigToxValDB_ECHA_IUCLID

Showing 9 of 9 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered(3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate280-734-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
1.5%
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1)?

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) has 9 NOAEL studies in the database. The lowest reported value is UM91A54Z8G UNII. Source: openFDA substances.

What regulatory lists include Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1)?

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Europe; Personal care - hair coloring. Source: EPA CPDat.

Is Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) used in cosmetics?

Yes, Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) is also indexed as a cosmetic ingredient under the name 2-Amino-4-Hydroxyethylaminoanisole Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) have different safety status in cosmetics vs industrial chemicals?

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) is prohibited in EU cosmetics at max 1.5% but has active industrial GHS classifications (H302, H315, H317, H319, H373, H400, H410, H411).

Is Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) used outside industrial chemicals?

Ethanol, 2-​[(3-​amino-​4-​methoxyphenyl)​amino]​-​, sulfate (1:1) also appears in cosmetics databases.