What is the NOAEL for Beta-Sitosterol?
Beta-Sitosterol has 5 NOAEL studies in the database. The lowest reported value is S347WMO6M4 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Beta-Sitosterol
Also known as: Stigmast-5-en-3-ol, (3β)-, (-)-β-Sitosterol, (24R)-Ethylcholest-5-en-3β-ol, (24R)-Stigmast-5-en-3β-ol, 22,23-Dihydrostigmasterol (+15 more)
CAS 83-46-5
Beta-Sitosterol (CAS 83-46-5) is a chemical substance. Key regulatory status: 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Beta-Sitosterol
CAS Number
83-46-5
DTXSID
DTXSID5022481
Molecular Formula
C29H50O
InChI Key
KZJWDPNRJALLNS-VJSFXXLFSA-N
Monoisotopic Mass
414.386166
Synonyms
Stigmast-5-en-3-ol, (3β)-(-)-β-Sitosterol(24R)-Ethylcholest-5-en-3β-ol(24R)-Stigmast-5-en-3β-ol22,23-Dihydrostigmasterol24α-EthylcholesterolAngelicinAzuprostatBetaprostCincholCupreolNimbosterol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
DeodorizerSoftener and conditionerStabilizing agentEmulsifierFragrancePharmaceutical
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| detected; wastewater | USGS | United States Geological Survey (USGS) |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| Canada; pharmaceutical | DrugBank | DrugBank |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| S347WMO6M4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S347WMO6M4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S347WMO6M4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S347WMO6M4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =2571 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BETA-SITOSTEROL
ChEMBL Phase
Not listed
Adverse Events
1
Bioactivity
16
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Beta-Sitosterol?
Beta-Sitosterol appears on 4 regulatory/inventory lists including detected; wastewater, detected; drinking_water; MN Chemical Screening, Canada; pharmaceutical, and 1 more. Source: EPA CPDat.
Is Beta-Sitosterol used in cosmetics?
Yes, Beta-Sitosterol is also indexed as a cosmetic ingredient under the name Beta-Sitosterol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Beta-Sitosterol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Beta-Sitosterol used outside industrial chemicals?
Beta-Sitosterol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.