What is the NOAEL for HC Violet no. 1?
HC Violet no. 1 has 13 NOAEL studies in the database. The lowest reported value is 800 mg/kg bw/day via oral in rat. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.
NOAEL Data
REACH Registered
Cosmetic Ingredient
HC Violet no. 1
Also known as: UNII-0R7XO4T22K, 4-Amino-3-methyl-4-(2-hydroxyethyl)amino-6-nitrobenzene, Ethanol, 2-((4-amino-2-methyl-5-nitrophenyl)amino)-, HC Violet 1, Imexine FAA
CAS 82576-75-8
HC Violet no. 1 (CAS 82576-75-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.
Cross-Vertical Regulatory Divergence
HC Violet no. 1 is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
HC Violet no. 1
CAS Number
82576-75-8
DTXSID
DTXSID50231887
Molecular Formula
C9H13N3O3
InChI Key
LGZSBRSLVPLNTM-UHFFFAOYSA-N
Monoisotopic Mass
211.095691
Synonyms
UNII-0R7XO4T22K4-Amino-3-methyl-4-(2-hydroxyethyl)amino-6-nitrobenzeneEthanol, 2-((4-amino-2-methyl-5-nitrophenyl)amino)-HC Violet 1Imexine FAA
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 800 | mg/kg bw/day | - | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 800 | mg/kg bw/day | - | - | - | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 0R7XO4T22K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0R7XO4T22K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0R7XO4T22K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0R7XO4T22K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 50 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =800 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =800 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =800 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =800 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| 800 | mg/kg bw/day | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 800 | mg/kg bw/d | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-(4-amino-2-methyl-5-nitroanilino)ethanol | 417-600-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
SCCS Opinions
EU Scientific Committee opinions tied to the matched substance.
SOURCE
EU SCCS
1 opinions
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCP/0939/05 | 20 June 2006 | safe | 0.25% | secondary amine; nitrosamine <50ppb; sensitisation not excluded |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include HC Violet no. 1?
HC Violet no. 1 appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.
Is HC Violet no. 1 used in cosmetics?
Yes, HC Violet no. 1 is also indexed as a cosmetic ingredient under the name HC Violet No. 1. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for HC Violet no. 1 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does HC Violet no. 1 have different safety status in cosmetics vs industrial chemicals?
HC Violet no. 1 is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Is HC Violet no. 1 used outside industrial chemicals?
HC Violet no. 1 also appears in cosmetics databases.