What is the NOAEL for Valeriana officinalis L., root extract?
Valeriana officinalis L., root extract has 6 NOAEL studies in the database. The lowest reported value is JWF5YAW3QW UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Valeriana officinalis L., root extract
Also known as: Valerian Root Extract, Valerian, Valerian extract
CAS 8057-49-6
Valeriana officinalis L., root extract (CAS 8057-49-6) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Valeriana Officinalis Collina Root Extract →
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Valeriana officinalis L., root extract
CAS Number
8057-49-6
DTXSID
DTXSID001017359
Synonyms
Valerian Root ExtractValerianValerian extract
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
DeodorizerSoftener and conditionerHumectantFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| JWF5YAW3QW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JWF5YAW3QW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JWF5YAW3QW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JWF5YAW3QW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 18600 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
134
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Valeriana officinalis L., root extract?
Valeriana officinalis L., root extract appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Valeriana officinalis L., root extract used in cosmetics?
Yes, Valeriana officinalis L., root extract is also indexed as a cosmetic ingredient under the name Valeriana Officinalis Collina Root Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Valeriana officinalis L., root extract come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Valeriana officinalis L., root extract used outside industrial chemicals?
Valeriana officinalis L., root extract also appears in cosmetics, pharmaceutical, food safety databases.