What is the NOAEL for Orange terpenes?
Orange terpenes has 6 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Orange terpenes
Also known as: EINECS 232-433-8, FEMA No. 2824, FEMA No. 2825, Orange oil, folded, Orange oil, sweet cold pressed (Citrus sinensis (L.) Osbeck) (+2 more)
CAS 8028-48-6
Orange terpenes (CAS 8028-48-6) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Citrus Aurantium Dulcis Flower Extract →
Cross-Vertical Regulatory Divergence
Orange terpenes is classified GHS Danger (H225, H226, H304, H315, H317, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
10
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Orange terpenes
CAS Number
8028-48-6
DTXSID
DTXSID1047730
Synonyms
EINECS 232-433-8FEMA No. 2824FEMA No. 2825Orange oil, foldedOrange oil, sweet cold pressed (Citrus sinensis (L.) Osbeck)Orange peel extract, sweet (Citrus sinensis (L.) Osbeck)Orange, sweet, ext.
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceAbrasiveSoftener and conditionerAntioxidantHumectantAstringentDeodorizerFlavouring and nutrientViscosity modifierEmulsifierBinderSolvent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =31.1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 6480 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Orange, sweet, ext. | 232-433-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Plant Extract
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Orange terpenes?
Orange terpenes appears on 6 regulatory/inventory lists including Europe; Personal care - hair styling and care - shampoo-dandruff, Europe; Personal care, IFRA Transparency, and 3 more. Source: EPA CPDat.
Is Orange terpenes used in cosmetics?
Yes, Orange terpenes is also indexed as a cosmetic ingredient under the name Citrus Aurantium Dulcis Flower Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Orange terpenes come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Orange terpenes have different safety status in cosmetics vs industrial chemicals?
Orange terpenes is classified GHS Danger (H225, H226, H304, H315, H317, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
Is Orange terpenes used outside industrial chemicals?
Orange terpenes also appears in cosmetics, cannabis databases.