What is the NOAEL for Oils, Orange, sweet?
Oils, Orange, sweet has 20 NOAEL studies in the database. The lowest reported value is AJ56JP5TFP UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Oils, Orange, sweet
Also known as: Absolue orange flower, Absolue orange flower decoloree, Absolue orange flower from water, Absolute orange flowers, Absolute petitgrain (+15 more)
CAS 8008-57-9
Oils, Orange, sweet (CAS 8008-57-9) is a chemical substance. Key regulatory status: 23 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Citrus Aurantium Dulcis Peel Oil →
SOURCE
noael studies public
NOAEL studies
20
SOURCE
chemical inventory jurisdictions
Regulatory lists
23
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Oils, Orange, sweet
CAS Number
8008-57-9
DTXSID
DTXSID1027685
Synonyms
Absolue orange flowerAbsolue orange flower decoloreeAbsolue orange flower from waterAbsolute orange flowersAbsolute petitgrainCaswell No. 425ACitrus sinensis OilCitrus sinensis peel oilFEMA No. 2822Neat oil of sweet orangeOil of sweet orangeOil sweet orange
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceCleaning agentDeodorizerSoftener and conditionerBiocideAstringentHumectant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
23 records
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - dental care - toothpaste | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| consumer_product | P&G | Proctor & Gamble |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; Personal care - body oil | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 20 of 20 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| AJ56JP5TFP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AJ56JP5TFP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AJ56JP5TFP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AJ56JP5TFP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AKN3KSD11B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AKN3KSD11B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AKN3KSD11B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AKN3KSD11B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H4QNH2ZN7A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H4QNH2ZN7A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H4QNH2ZN7A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H4QNH2ZN7A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 12960 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =375 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_HPVIS |
| =1500 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_HPVIS |
| >2500 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_HPVIS |
| =240 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =750 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 20 of 20 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
Annex III Entry 351: declare if >0.001% leave-on or >0.01% rinse-off. Furocoumarin <1 mg/kg in sun-protection. Max 15 ppm 5-MOP.
Category
essential oil
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Oils, Orange, sweet?
Oils, Orange, sweet appears on 12 regulatory/inventory lists including children; Europe; Personal care, children; Europe; Personal care - dental care - toothpaste, Europe; Personal care, and 9 more. Source: EPA CPDat.
Is Oils, Orange, sweet used in cosmetics?
Yes, Oils, Orange, sweet is also indexed as a cosmetic ingredient under the name Citrus Aurantium Dulcis Peel Oil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oils, Orange, sweet come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Oils, Orange, sweet used outside industrial chemicals?
Oils, Orange, sweet also appears in cosmetics, food safety databases.