What is the NOAEL for Mace oil?
Mace oil has 10 NOAEL studies in the database. The lowest reported value is 9KKX6I0U7Z UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Mace oil
Also known as: FEMA No. 2652, FEMA No. 2653, FEMA No. 2654, Mace (Myristica fragrans Houtt.), Mace oil (Myristica fragrans Houtt.) (+13 more)
CAS 8007-12-3
Mace oil (CAS 8007-12-3) is a chemical substance. Key regulatory status: 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Myristica Fragrans Kernel Oil →
SOURCE
NOAEL studies
NOAEL studies
10
SOURCE
Chemical inventory jurisdictions
Regulatory lists
13
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Mace oil
CAS Number
8007-12-3
DTXSID
DTXSID9093692
Synonyms
FEMA No. 2652FEMA No. 2653FEMA No. 2654Mace (Myristica fragrans Houtt.)Mace oil (Myristica fragrans Houtt.)Mace oleoresin/extract (Myristica fragrans Houtt.)Macis oilNCI-C56484Nutmeg butterNutmeg butter fatNutmeg fatNutmeg oil, expressed
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
FragranceDeodorizerSoftener and conditionerThickening agentFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| IFRA Transparency | IFRA | IFRA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| IFRA Transparency | IFRA | IFRA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 9KKX6I0U7Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9KKX6I0U7Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9KKX6I0U7Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9KKX6I0U7Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 5400 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| >=260 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| >=560 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| >=600 | mg/kg bw/day | NOAEL | oral | Hamster | ECHA |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 10 of 10 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Plant Oil / Essential Oil
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Mace oil?
Mace oil appears on 4 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency, consumer_product, and 1 more. Source: EPA CPDat.
Is Mace oil used in cosmetics?
Yes, Mace oil is also indexed as a cosmetic ingredient under the name Myristica Fragrans Kernel Oil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Mace oil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Mace oil used outside industrial chemicals?
Mace oil also appears in cosmetics, food safety databases.