NOAEL Data Cosmetic Ingredient

2-Nitro-5-glyceryl methylaniline

CAS 80062-31-3

2-Nitro-5-glyceryl methylaniline (CAS 80062-31-3) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS.

View cosmetic safety profile for 2-Nitro-5-Glyceryl Methylaniline →

SOURCE noael studies public
NOAEL studies
80
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
2-Nitro-5-glyceryl methylaniline
CAS Number
80062-31-3
DTXSID
DTXSID50868556
Molecular Formula
C10H14N2O5
InChI Key
CDRHDQOGKXFJSA-UHFFFAOYSA-N
Monoisotopic Mass
242.090272

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
Europe; Personal care; restrictedEuropean CommissionCosIng
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 80 studies
ValueUnitEndpointRouteSpeciesSource
100mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
100mg/kg bw---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
300mg/kg/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
300mg/kg/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
300mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
300mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
800mg/kg bw/day---UnifiedCodex:SCCS_SHADOW:beta.noael_studies
Y6YE3133F5UNIIFDA UNII substance identifier--openFDA substances
Y6YE3133F5UNIIFDA UNII substance identifier--openFDA substances
Y6YE3133F5UNIIFDA UNII substance identifier--openFDA substances
Y6YE3133F5UNIIFDA UNII substance identifier--openFDA substances
50mg/kg bw/dayLOAELoralratCOSMOS_DB
=0.011mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.011mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.011mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.011mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.04mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.04mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.04mg/kg bw/dNOAELoralratSCCS_vision_codex
=0.04mg/kg bw/dNOAELoralratSCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg/dayNOAELoralratSCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg/dayNOAELoralratSCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg/dayNOAELoralratSCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=50mg/kg/dayNOAELoralratSCCS_vision_codex
=50mg/kg bwNOAEL--SCCS_vision_codex
=100mg/kg bw/dayNOAEL--SCCS_vision_codex
=100mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=100mg/kg bwNOAELoralrabbitSCCNFP_vision_codex
=100mg/kg bw/dayNOAEL--SCCS_vision_codex
=100mg/kg bw/dayNOAEL--SCCS_vision_codex
=100mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=100mg/kg bwNOAELoralrabbitSCCNFP_vision_codex
=100mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=100mg/kg bwNOAELoralrabbitSCCNFP_vision_codex
=100mg/kg bw/dayNOAEL--SCCS_vision_codex
=100mg/kg bw/dayNOAELdermal-SCCNFP_vision_codex
=100mg/kg bwNOAELoralrabbitSCCNFP_vision_codex
=200mg/kg bw/dNOAEL--SCCS_vision_codex
=200mg/kg bw/dNOAEL--SCCS_vision_codex
=200mg/kg bw/dNOAEL--SCCS_vision_codex
=200mg/kg bw/dNOAEL--SCCS_vision_codex
=300mg/kg/dayNOAEL--SCCS_vision_codex
=300mg/kg bw/dayNOAEL--SCCS_vision_codex

Showing 50 of 80 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE EU SCCS 2 opinions
OpinionDateConclusionMax Conc.Concerns
SCCS/1476/1218 September 2012safe with restrictions0.8% oxidative / 1.0% non-oxidativesecondary amine; sensitisation not excluded; nitrosamine <50ppb
SCCP/1202/0821 January 2009safe with restrictions2.0%secondary amine; nitrosamine <50ppb; sensitisation not excluded

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
1.0%
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 2-Nitro-5-glyceryl methylaniline?

2-Nitro-5-glyceryl methylaniline has 80 NOAEL studies in the database. The lowest reported value is 0.011 mg/kg bw/d via oral in rat. Source: SCCS_vision_codex.

What regulatory lists include 2-Nitro-5-glyceryl methylaniline?

2-Nitro-5-glyceryl methylaniline appears on 2 regulatory/inventory lists including Europe; Personal care; restricted, children; Europe; Personal care. Source: EPA CPDat.

Is 2-Nitro-5-glyceryl methylaniline used in cosmetics?

Yes, 2-Nitro-5-glyceryl methylaniline is also indexed as a cosmetic ingredient under the name 2-Nitro-5-Glyceryl Methylaniline. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Nitro-5-glyceryl methylaniline come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does 2-Nitro-5-glyceryl methylaniline have different safety status in cosmetics vs industrial chemicals?

2-Nitro-5-glyceryl methylaniline is prohibited in EU cosmetics at max 1.0% but has active industrial GHS classifications (H302).

Is 2-Nitro-5-glyceryl methylaniline used outside industrial chemicals?

2-Nitro-5-glyceryl methylaniline also appears in cosmetics databases.