What is the NOAEL for Lanolin?
Lanolin has 11 NOAEL studies in the database. The lowest reported value is 7EV65EAW6H UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Lanolin
Also known as: Caswell No. 518, EINECS 232-348-6, EPA Pesticide Chemical Code 031601, Fats and Glyceridic oils, lanoline, Wollfett (+15 more)
CAS 8006-54-0
Lanolin (CAS 8006-54-0) is a chemical substance. Key regulatory status: 18 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
18
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Lanolin
CAS Number
8006-54-0
DTXSID
DTXSID2027678
Synonyms
Caswell No. 518EINECS 232-348-6EPA Pesticide Chemical Code 031601Fats and Glyceridic oils, lanolineWollfettAdeps lanaeAdeps Lanae ahydricusLanae ceraUNII-7EV65EAW6HLantrol 1674Lantrol 1673Lanor crystal
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Softener and conditionerHumectantSurfactant (surface active agent)Anti-static agentEmulsifierSolventStabilizing agentBinderFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
18 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Cleaning products and household care - shoes; Europe | Danish Environmental Protection Agency | Danish EPA |
| Cleaning products and household care - shoes; Europe | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - make-up and related | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - make-up and related | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7EV65EAW6H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7EV65EAW6H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7EV65EAW6H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7EV65EAW6H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 15520 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
10
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Lanolin?
Lanolin appears on 13 regulatory/inventory lists including active_ingredient; Europe; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 10 more. Source: EPA CPDat.
Is Lanolin used in cosmetics?
Yes, Lanolin is also indexed as a cosmetic ingredient under the name Lanolin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Lanolin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Lanolin used outside industrial chemicals?
Lanolin also appears in cosmetics, pharmaceutical, food safety databases.