What is the NOAEL for Cyclotene?
Cyclotene has 7 NOAEL studies in the database. The lowest reported value is 627E92X64B UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Cyclotene
Also known as: Maple lactone, 2-Hydroxy-3-methylcyclopent-2-en-1-one, BRN 2039308, Corylon, Corylone (+11 more)
CAS 80-71-7
Cyclotene (CAS 80-71-7) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Cyclotene
CAS Number
80-71-7
DTXSID
DTXSID4035128
Molecular Formula
C6H8O2
InChI Key
CFAKWWQIUFSQFU-UHFFFAOYSA-N
Monoisotopic Mass
112.052429
Synonyms
Maple lactone2-Hydroxy-3-methylcyclopent-2-en-1-oneBRN 2039308CorylonCoryloneCyclotenEINECS 201-303-22-Hydroxy-3-methyl-2-cyclopenten-1-one3-Methylcyclopentane-1,2-dione3-Methyl-2-cyclopentene-2-ol-1-oneNSC 1334453-Methylcyclopent-2-en-2-ol-1-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
48 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5.18 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =200 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-hydroxy-3-methylcyclopent-2-enone | 201-303-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
101
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Cyclotene?
Cyclotene appears on 2 regulatory/inventory lists including Europe, IFRA Transparency. Source: EPA CPDat.
Is Cyclotene used in cosmetics?
Yes, Cyclotene is also indexed as a cosmetic ingredient under the name METHYLCYCLOPENTENOLONE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cyclotene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Cyclotene used outside industrial chemicals?
Cyclotene also appears in cosmetics, pharmaceutical, cannabis databases.