Also known as: 2-Propenoic acid, Acroleic acid, LX 300 (crosslinking agent), 4-02-00-01455, Acrylic acid, glacial (+8 more)
CAS 79-10-7
Acrylic acid (CAS 79-10-7) is a chemical substance with GHS signal word Danger; key hazard signal: H226; H332; H312; H302; H314; H400. Key regulatory status: REACH registered, 14 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, IARC, ECHA REACH, ILO ICSC, OSHA, EPA TRI.
Acrylic acid is classified GHS Danger (H226, H332, H312, H302, H314, H400) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
Carcinogenic hazard classification from IARC monograph evaluations.
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1998 | 19, Sup 7, 71 |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A; Aquatic Acute 1 | H226; H332; H312; H302; H314; H400 | GHS02; GHS07; GHS05; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Flammable liquid and vapour Toxic if swallowed, in contact with skin or if inhaled Causes severe skin burns and eye damage May cause respiratory irritation Harmful to aquatic life |
| Short-term Effects | The substance is corrosive to the eyes and skin. Corrosive on ingestion. The vapour is severely irritating to the eyes and respiratory tract. |
| Long-term Effects | Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the upper respiratory tract and lungs. This may result in reduced lung function and hyperreactivity of the airways. See Notes. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation, through the skin and by ingestion. |
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| NIOSH | TWA | 2 ppm (6 mg/m³) | 2 | 6 | Y |
| ACGIH | TWA | 2 ppm [1986] | 2 | - | Y |
| CAL/OSHA | TWA | 2 ppm (5.9 mg/m³) | 2 | 5.9 | Y |
| AIHA | ERPG-1 | 1 ppm | 1 | - | - |
| AIHA | ERPG-2 | 50 ppm | 50 | - | - |
| AIHA | ERPG-3 | 250 ppm | 250 | - | - |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| detected; Europe; Personal care - nails - nail polish | Danish Environmental Protection Agency | Danish EPA |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.02 | mg/m3 | BMCL (10 HEC) | inhalation | Mouse | ToxValDB_PPRTV_(CPHEA) |
| 28 | min | Breakthrough Time | Dermal | - | NTP_ICE_skin_irritation |
| 29 | min | Breakthrough Time | Dermal | - | NTP_ICE_skin_irritation |
| =30 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| J94PBK7X8S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J94PBK7X8S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J94PBK7X8S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J94PBK7X8S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| 0.879 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 1.283 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 1.884 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 3.5346 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 3.6 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >4.31 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >5.1 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >6.74 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 7.7644 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 11.3403 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 16.6481 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =70737 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
| =14.94 | mg/m3 | LOAEL | inhalation | Mouse | ToxValDB_IRIS |
| =15 | mg/m3 | LOAEL | inhalation | Mouse | INCHEM_WHO_hsg_hsg_v104hsg |
| =15 | mg/m3 | LOAEL | inhalation | - | INCHEM_WHO_ehc_ehc_ehc191 |
| =15 | mg/m3 | LOAEL | inhalation | Mouse | INCHEM_WHO_hsg_hsg_v104hsg |
| =150 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =240 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_IRIS |
| =250 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =2.67 | mg/m3 | LOAEL (ADJ) | inhalation | Mouse | ToxValDB_IRIS |
| =0.33 | mg/m3 | LOAEL (HEC) | inhalation | Mouse | ToxValDB_IRIS |
| =0.33 | mg/m^3 | LOAEL (HEC) | inhalation | - | EPA_IRIS_iris_rfc_systems.csv |
| =0.6 | % | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =4 | % | LOEL | dermal | Mouse | ToxValDB_ECOTOX |
| =8 | % w/v | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =100 | ul/org | LOEL | dermal | Mouse | ToxValDB_ECOTOX |
| =730 | mg/L | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =5000 | mg/L | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =40 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =53 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_IRIS |
| =53 | mg/kg/day | NOAEL | oral | - | EPA_IRIS_iris_rfd_systems.csv |
| =66 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =73.6844 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_EU_SCOEL |
| =73.6844 | mg/m3 | NOAEL | inhalation | Rabbit | ToxValDB_HPVIS |
| =78 | mg/kg bw/day | NOAEL | oral | - | INCHEM_WHO_ehc_ehc_ehc191 |
| =83 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =140 | mg/kg bw/day | NOAEL | inhalation | Rat; Mouse | INCHEM_WHO_ehc_ehc_ehc191 |
| =140 | mg/kg bw | NOAEL | - | Rat | INCHEM_WHO_ehc_ehc_ehc191 |
| =235.79 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_Cal_OEHHA_REL_derivations |
| =240 | mg/kg bw/day | NOAEL | - | - | INCHEM_WHO_ehc_ehc_ehc191 |
Showing 50 of 100 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Acrylic acid | 201-177-9 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| Acrylic acid | - | - |
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Acrylic acid (CAS 79-10-7) is classified under EU CLP Annex VI as Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1A; Aquatic Acute 1 with signal word Danger. Hazard statements: H226; H332; H312; H302; H314; H400. Source: EU CLP Annex VI (ECHA).
Acrylic acid has 100 NOAEL studies in the database. The lowest reported value is -1.1 % via Dermal. Source: NTP_ICE_skin_irritation.
Acrylic acid appears on 8 regulatory/inventory lists including detected; Europe; Personal care - nails - nail polish, drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; Pesticides, and 5 more. Source: EPA CPDat.
Acrylic acid is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1998). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Occupational exposure limits for Acrylic acid are set by NIOSH, ACGIH, CAL/OSHA. 6 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Yes, Acrylic acid is also indexed as a cosmetic ingredient under the name ACRYLIC ACID. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, IARC Monographs, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Acrylic acid is classified GHS Danger (H226, H332, H312, H302, H314, H400) in the chemicals database but is allowed in EU cosmetics.
Acrylic acid also appears in cosmetics, pharmaceutical, cannabis databases.