Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Triethyl phosphate

Also known as: BRN 1705772, EINECS 201-114-5, Triethylfosfat, UNII-QIH4K96K7J, TEP (+3 more)

CAS 78-40-0

Triethyl phosphate (CAS 78-40-0) is a chemical substance with GHS signal word Warning; key hazard signal: H302. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Triethyl Phosphate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields

Name

Triethyl phosphate

CAS Number

78-40-0

DTXSID

DTXSID8026228

Molecular Formula

C6H15O4P

InChI Key

DQWPFSLDHJDLRL-UHFFFAOYSA-N

Monoisotopic Mass

182.070796

Synonyms

BRN 1705772EINECS 201-114-5TriethylfosfatUNII-QIH4K96K7JTEPTriethylphosphateTris(ethyl) phosphateo-Phosphoric acid triethyl ester

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Acute Tox. 4 *	H302	GHS07	Warning

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
GHS Signal Word	WARNING
GHS Hazard Statements	Harmful if swallowed May cause drowsiness or dizziness
Short-term Effects	The substance is mildly irritating to the eyes. The substance may cause effects on the central nervous system.
Routes of Exposure	The substance can be absorbed into the body by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 9 records

SolventFlame retardantPlasticizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 7 records

List	Keyword	Source
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
CEDI	FDA	United States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)	FDA	United States Food and Drug Administration (FDA)
Europe; plastic_additive	European Chemicals Agency	European Chemicals Agency (ECHA)
Canada; pharmaceutical	DrugBank	DrugBank
detected; Europe; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 29 of 29 studies

Value	Unit	Endpoint	Route	Species	Source
=9.9	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
QIH4K96K7J	UNII	FDA UNII substance identifier	-	-	openFDA substances
QIH4K96K7J	UNII	FDA UNII substance identifier	-	-	openFDA substances
QIH4K96K7J	UNII	FDA UNII substance identifier	-	-	openFDA substances
QIH4K96K7J	UNII	FDA UNII substance identifier	-	-	openFDA substances
=1165	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=1600	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
~67	mg/kg bw/day	LEL	oral	Rat	ToxValDB_ECHA_IUCLID
=250	mg/kg bw/day	LEL	oral	Dog	ToxValDB_ECHA_IUCLID
=333	mg/kg bw/day	LEL	injection	Rat	ToxValDB_ECHA_IUCLID
=412	mg/kg bw/day	LEL	injection	Rat	ToxValDB_ECHA_IUCLID
=437	mg/kg bw/day	LEL	injection	Rat	ToxValDB_ECHA_IUCLID
=495	mg/kg bw/day	LEL	injection	Rat	ToxValDB_ECHA_IUCLID
=600	mg/kg bw/day	LEL	injection	Mouse	ToxValDB_ECHA_IUCLID
=1000	mg/kg bw/day	LEL	oral	Rat	ToxValDB_ECHA_IUCLID
=2000	mg/kg bw/day	LEL	oral	Chicken	ToxValDB_ECHA_IUCLID
=89402.2	mg/m3	LEL	inhalation	Human	ToxValDB_DOE_Protective_Action_Criteria
=250	mg/kg bw/day	LOAEL	oral	Rabbit	ToxValDB_EPA_TSCA_8e
=330	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
-	unitless	Model Score	-	-	NTP_ICE_endocrine
=366	mg/m3	NOAEC	inhalation	Rat	ToxValDB_ECHA_IUCLID
>10	mg/kg bw/day	NOAEL	injection	Chicken	ToxValDB_ECHA_IUCLID
=80	mg/kg bw/day	NOAEL	oral	Rabbit	ToxValDB_ECHA_IUCLID
=125	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=200	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=250	mg/kg bw/day	NOAEL	oral	Rabbit	ToxValDB_ECHA_IUCLID
~335	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=625	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
>=700	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID

Showing 29 of 29 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Triethyl phosphate	201-114-5	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL TRIETHYL PHOSPHATE

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Triethyl phosphate?

Triethyl phosphate (CAS 78-40-0) is classified under EU CLP Annex VI as Acute Tox. 4 * with signal word Warning. Hazard statements: H302. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Triethyl phosphate?

Triethyl phosphate has 29 NOAEL studies in the database. The lowest reported value is 9.9 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Triethyl phosphate?

Triethyl phosphate appears on 6 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, CEDI, Indirect additives food contact (10/2018), and 3 more. Source: EPA CPDat.

Is Triethyl phosphate used in cosmetics?

Yes, Triethyl phosphate is also indexed as a cosmetic ingredient under the name Triethyl Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Triethyl phosphate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Triethyl phosphate used outside industrial chemicals?

Triethyl phosphate also appears in cosmetics, pharmaceutical databases.