What is the NOAEL for Manganese dichloride?
Manganese dichloride has 23 NOAEL studies in the database. The lowest reported value is 0.2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Manganese dichloride
Also known as: MnCl2, Manganese chloride anhydrous, Manganese chloride (MnCl2), Manganese(II) chloride, Manganese chloride (+6 more)
CAS 7773-01-5
Manganese dichloride (CAS 7773-01-5) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Manganese dichloride is classified GHS Danger (H301, H302, H318, H373, H411, H372, H341, H360) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
23
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Manganese dichloride
CAS Number
7773-01-5
DTXSID
DTXSID9040681
Molecular Formula
2ClH.Mn
InChI Key
GLFNIEUTAYBVOC-UHFFFAOYSA-L
Monoisotopic Mass
126.891399
Synonyms
MnCl2Manganese chloride anhydrousManganese chloride (MnCl2)Manganese(II) chlorideManganese chlorideEINECS 231-869-6ScacchiteUNII-6YB4901Y90Manganese bichloridemanganese(II) dichloridemanganous dichloride
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 23 of 23 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 6YB4901Y90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6YB4901Y90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6YB4901Y90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6YB4901Y90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.5 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =1 | mg/L | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =2 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =2 | ppm | LEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =8 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =14.84 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =15 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =20 | mg/L | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =59.36 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | LEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| <=150 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =12.5 | mg/kg bw/day | LOAEC | injection | Mouse | ToxValDB_ECHA_IUCLID |
| =250 | umol/kg bw | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =3.9 | mg/m3 | NOAEC | inhalation | Rabbit | ToxValDB_ECHA_IUCLID |
| =2 | mg/kg bw/day | NOAEL | injection | Mouse | ToxValDB_ECHA_IUCLID |
| =16 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =15000 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 23 of 23 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Manganese dichloride | 231-869-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
manganese chloride
ChEMBL Phase
Not listed
Adverse Events
28
Bioactivity
0
Frequently Asked Questions
Is Manganese dichloride used in cosmetics?
Yes, Manganese dichloride is also indexed as a cosmetic ingredient under the name Manganese Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Manganese dichloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Manganese dichloride have different safety status in cosmetics vs industrial chemicals?
Manganese dichloride is classified GHS Danger (H301, H302, H318, H373, H411, H372, H341, H360) in the chemicals database but is allowed in EU cosmetics.
Is Manganese dichloride used outside industrial chemicals?
Manganese dichloride also appears in cosmetics, pharmaceutical databases.