What is the NOAEL for Trimagnesium phosphate?
Trimagnesium phosphate has 6 NOAEL studies in the database. The lowest reported value is XMK14ETW2D UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Trimagnesium phosphate
Also known as: Phosphoric acid, magnesium salt (2:3), Trimagnesium bis(orthophosphate), Magnesium phosphate, tribasic, Magnesium phosphate, tribasic, anhydrous, EC 231-824-0 (+6 more)
CAS 7757-87-1
Trimagnesium phosphate (CAS 7757-87-1) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Trimagnesium phosphate is classified GHS Danger (H302, H311, H314, H331, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Trimagnesium phosphate
CAS Number
7757-87-1
DTXSID
DTXSID00872527
Molecular Formula
3Mg.2H3O4P
InChI Key
GVALZJMUIHGIMD-UHFFFAOYSA-H
Monoisotopic Mass
267.908916
Synonyms
Phosphoric acid, magnesium salt (2:3)Trimagnesium bis(orthophosphate)Magnesium phosphate, tribasicMagnesium phosphate, tribasic, anhydrousEC 231-824-0EINECS 231-824-0HSDB 1005UNII-XMK14ETW2DMagnesium phosphate anhydrousMagnesium orthophosphateMagnesium phosphate (Mg3(PO4)2)
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
OpaciferFillerAnti-caking agentPigmentThickening agentpH regulating agentFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| XMK14ETW2D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK14ETW2D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK14ETW2D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK14ETW2D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =145.7 | mg/kg bw/day | NOAEL | oral | Human | ToxValDB_PPRTV_(CPHEA) |
| =49 | mg/kg bw/day | RfD (provisional) | oral | Human | ToxValDB_PPRTV_(CPHEA) |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Trimagnesium bis(orthophosphate) | 231-824-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MAGNESIUM PHOSPHATE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E343 — ADI: 40 mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Trimagnesium phosphate?
Trimagnesium phosphate appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), inert_ingredient; Pesticides, and 2 more. Source: EPA CPDat.
Is Trimagnesium phosphate used in cosmetics?
Yes, Trimagnesium phosphate is also indexed as a cosmetic ingredient under the name Trimagnesium Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Trimagnesium phosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does Trimagnesium phosphate have different safety status in cosmetics vs industrial chemicals?
Trimagnesium phosphate is classified GHS Danger (H302, H311, H314, H331, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Trimagnesium phosphate used outside industrial chemicals?
Trimagnesium phosphate also appears in cosmetics, pharmaceutical, food safety databases.