NOAEL Data REACH Registered Cosmetic Ingredient

Basic Red 51

Also known as: 1H-Imidazolium, 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-, chloride (1:1)

CAS 77061-58-6

Basic Red 51 (CAS 77061-58-6) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.

View cosmetic safety profile for Basic Red 51 →

Cross-Vertical Regulatory Divergence

Basic Red 51 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H400, H410).

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

100

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields

Name

Basic Red 51

CAS Number

77061-58-6

DTXSID

DTXSID80874049

Molecular Formula

C13H18N5.ClH

InChI Key

NZDXSXLYLMHYJA-UHFFFAOYSA-M

Monoisotopic Mass

280.132898

Synonyms

1H-Imidazolium, 2-[2-[4-(dimethylamino)phenyl]diazenyl]-1,3-dimethyl-, chloride (1:1)

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records

Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 6 records

List	Keyword	Source
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair coloring	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair coloring	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair coloring	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair coloring	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care; restricted	European Commission	CosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 100 studies

Value	Unit	Endpoint	Route	Species	Source
A7A946JJ6I	UNII	FDA UNII substance identifier	-	-	openFDA substances
A7A946JJ6I	UNII	FDA UNII substance identifier	-	-	openFDA substances
A7A946JJ6I	UNII	FDA UNII substance identifier	-	-	openFDA substances
A7A946JJ6I	UNII	FDA UNII substance identifier	-	-	openFDA substances
10	mg/kg bw/day	LOAEL	oral	rat	COSMOS_DB
=0.005	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.005	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.005	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.005	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.006	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.006	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.006	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=0.006	mg/kg	NOAEL	oral	rat	SCCS_vision_codex
=10	mg/kg bw/day	NOAEL	-	-	SCCS_vision_codex
=10	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=10	mg/kg/day	NOAEL	dermal	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	-	-	SCCS_vision_codex
=10	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=10	mg/kg bw/day	NOAEL	-	-	SCCS_vision_codex
=10	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=10	mg/kg/day	NOAEL	dermal	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=10	mg/kg/day	NOAEL	dermal	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	-	-	SCCS_vision_codex
=10	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=10	mg/kg/day	NOAEL	dermal	-	SCCNFP_vision_codex
=10	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCS_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCNFP_vision_codex
=12.25	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCS_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCS_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCNFP_vision_codex
=12.25	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCNFP_vision_codex
=12.25	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCS_vision_codex
=12.25	mg/kg	NOAEL	dermal	rat	SCCNFP_vision_codex
=12.25	mg/kg bw/day	NOAEL	oral	-	SCCNFP_vision_codex
=20	mg/kg bw/day	NOAEL	oral	mouse	SCCS_vision_codex
=20	mg/kg bw/day	NOAEL	-	human	SCCNFP_vision_codex
=20	mg/kg bw/day	NOAEL	oral	mouse	SCCS_vision_codex
=20	mg/kg bw/day	NOAEL	oral	mouse	SCCS_vision_codex
=20	mg/kg bw/day	NOAEL	-	human	SCCNFP_vision_codex
=20	mg/kg bw/day	NOAEL	-	human	SCCNFP_vision_codex
=20	mg/kg bw/day	NOAEL	oral	mouse	SCCS_vision_codex
=20	mg/kg bw/day	NOAEL	-	human	SCCNFP_vision_codex
=50	mg/kg bw/d	NOAEL	-	-	SCCS_vision_codex

Showing 50 of 100 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	2-[[4-(dimethylamino)phenyl]azo]-1,3-dimethyl-1H-imidazolium chloride	278-601-4	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE EU SCCS 1 opinions

Opinion	Date	Conclusion	Max Conc.	Concerns
SCCS/1445/11	20 September 2011	safe	0.5%	sensitisation potential; tertiary amine

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

prohibited

Max

Frequently Asked Questions

What is the NOAEL for Basic Red 51?

Basic Red 51 has 100 NOAEL studies in the database. The lowest reported value is A7A946JJ6I UNII. Source: openFDA substances.

What regulatory lists include Basic Red 51?

Basic Red 51 appears on 3 regulatory/inventory lists including children; Europe; Personal care, Europe; Personal care - hair coloring, Europe; Personal care; restricted. Source: EPA CPDat.

Is Basic Red 51 used in cosmetics?

Yes, Basic Red 51 is also indexed as a cosmetic ingredient under the name Basic Red 51. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Basic Red 51 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Basic Red 51 have different safety status in cosmetics vs industrial chemicals?

Basic Red 51 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H400, H410).

Is Basic Red 51 used outside industrial chemicals?

Basic Red 51 also appears in cosmetics databases.