What is the NOAEL for 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate?
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate has 4 NOAEL studies in the database. The lowest reported value is 058C04BGYI UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate
Also known as: (-) Quinic acid, D-(−)-Quinic acid, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (-)-, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3R,4alpha,5R)-, (1S,3R,4S,5R)-1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid (+1 more)
CAS 77-95-2
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate (CAS 77-95-2) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate
CAS Number
77-95-2
DTXSID
DTXSID70998288
Molecular Formula
C7H12O6
InChI Key
AAWZDTNXLSGCEK-LNVDRNJUSA-M
Monoisotopic Mass
192.063388
Synonyms
(-) Quinic acidD-(−)-Quinic acidCyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (-)-Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3R,4alpha,5R)-(1S,3R,4S,5R)-1,3,4,5-Tetrahydroxycyclohexanecarboxylic acidQuinic acid
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
pH regulating agentFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 058C04BGYI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 058C04BGYI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 058C04BGYI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 058C04BGYI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1,3,4,5-tetrahydroxycyclohexanecarboxylic acid | 201-072-8 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
QUINIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate?
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate appears on 2 regulatory/inventory lists including Europe, active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate used in cosmetics?
Yes, 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate is also indexed as a cosmetic ingredient under the name Quinic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate used outside industrial chemicals?
1,3,4,5-Tetrahydroxycyclohexane-1-carboxylate also appears in cosmetics, pharmaceutical, cannabis databases.