What is the NOAEL for Gibberellic acid?
Gibberellic acid has 18 NOAEL studies in the database. The lowest reported value is 0 uL/min/10^6 cells in Human. Source: NTP ICE adme parameters.
NOAEL Data
Cosmetic Ingredient
Gibberellic acid
Also known as: Gibberellin, GA, 5-18-09-00269, Acide gibberellique, Activol GA (+15 more)
CAS 77-06-5
Gibberellic acid (CAS 77-06-5) is a chemical substance. Key regulatory status: 60 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
18
SOURCE
Chemical inventory jurisdictions
Regulatory lists
60
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Gibberellic acid
CAS Number
77-06-5
DTXSID
DTXSID0020656
Molecular Formula
C19H22O6
InChI Key
IXORZMNAPKEEDV-OBDJNFEBSA-N
Monoisotopic Mass
346.141638
Synonyms
GibberellinGA5-18-09-00269Acide gibberelliqueActivol GABrellinBRN 0054346Caswell No. 467Cekugib(3S,3aS,4S,4aS,6S,8aS,8bS,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid(3S,3aR,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propenoazuleno(1,2-b)furan-4-carboxylic acid(3S,3aS,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propeno(1,2-b)furan-4-carboxylic acid
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
60 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.68 | mg/kg bw/day | ADI | - | Consumers | EFSA |
| =0.68 | mg/kg bw/day | ADI | - | Consumers | EFSA |
| - | uL/min/10^6 cells | Clint | - | Human | NTP ICE adme parameters |
| - | uL/min/10^6 cells | Clint | - | Rat | NTP ICE adme parameters |
| BU0A7MWB6L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.24 | fraction | Fu | - | Human | NTP ICE adme parameters |
| 0.8015 | fraction | Fu | - | Rat | NTP ICE adme parameters |
| =0.0001 | mg/day | LEL | injection | Mouse | ToxValDB Uterotrophic Hershberger DB |
| 0.0001 | mg/day | LOEL | Subcutaneous | Mouse | NTP ICE endocrine |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
| =680 | mg/kg bw/day | NOAEL | oral | Rat | EFSA |
| =680 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA |
| =680 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA |
| =1000 | mg/kg bw/day | NOEL | oral | Rat | EFSA |
| =1000 | mg/kg bw/day | NOEL | - | Rabbit | EFSA |
| =1000 | mg/kg bw/day | NOEL | - | Rabbit | EFSA |
| 54 | % | Uterine weight increase vs control | Subcutaneous | Mouse | NTP ICE endocrine |
| 69 | % | Uterine weight increase vs control | Subcutaneous | Mouse | NTP ICE endocrine |
Showing 18 of 18 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
GIBBERELLIN A3
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Gibberellic acid?
Gibberellic acid appears on 7 regulatory/inventory lists including active_ingredient; agricultural; applied; Pesticides, active_ingredient; agricultural; Pesticides, active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides, and 4 more. Source: EPA CPDat.
Is Gibberellic acid used in cosmetics?
Yes, Gibberellic acid is also indexed as a cosmetic ingredient under the name Gibberellic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Gibberellic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Gibberellic acid used outside industrial chemicals?
Gibberellic acid also appears in cosmetics, pharmaceutical, cannabis databases.