What is the NOAEL for Sodium iodide?
Sodium iodide has 10 NOAEL studies in the database. The lowest reported value is 0.822 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium iodide
Also known as: NaI, Sodium iodide (NaI), Caswell No. 777, EINECS 231-679-3, EPA Pesticide Chemical Code 075702 (+2 more)
CAS 7681-82-5
Sodium iodide (CAS 7681-82-5) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Sodium iodide is classified GHS Danger (H315, H319, H335, H372, H400, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Sodium iodide
CAS Number
7681-82-5
DTXSID
DTXSID2041125
Molecular Formula
HI.Na
InChI Key
FVAUCKIRQBBSSJ-UHFFFAOYSA-M
Synonyms
NaISodium iodide (NaI)Caswell No. 777EINECS 231-679-3EPA Pesticide Chemical Code 075702Jodid sodnyUNII-F5WR8N145C
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. |
| Long-term Effects | Ingestion may cause effects on the thyroid. May cause systemic sensitization. See Notes. |
| Routes of Exposure | The substance can be absorbed into the body by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Biocide
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.822 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| F5WR8N145C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F5WR8N145C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F5WR8N145C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F5WR8N145C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3.7 | MBq | LOEL | injection | Rat | ToxValDB_ECOTOX |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =0.01 | mg/kg bw/day | NOAEL | oral | Human | ToxValDB_ATSDR_MRLs |
| =0.01 | mg/kg/day | NOAEL | oral | Human (M/F) | ATSDR_toxval_ATSDR_MRLs.xlsx |
| =0.6 | mg/L | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium iodide | 231-679-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM IODIDE
ChEMBL Phase
4
Adverse Events
236
Bioactivity
1
Frequently Asked Questions
What regulatory lists include Sodium iodide?
Sodium iodide appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Indirect additives food contact (10/2018), Europe; supplements, and 2 more. Source: EPA CPDat.
Is Sodium iodide used in cosmetics?
Yes, Sodium iodide is also indexed as a cosmetic ingredient under the name Sodium Iodide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium iodide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium iodide have different safety status in cosmetics vs industrial chemicals?
Sodium iodide is classified GHS Danger (H315, H319, H335, H372, H400, H411) in the chemicals database but is allowed in EU cosmetics.
Is Sodium iodide used outside industrial chemicals?
Sodium iodide also appears in cosmetics, pharmaceutical databases.