What is the NOAEL for Copper(I) iodide?
Copper(I) iodide has 18 NOAEL studies in the database. The lowest reported value is 0.07 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Copper(I) iodide
Also known as: Cuprous iodide, Copper iodide,, Copper iodide (CuI), EINECS 231-674-6, Hydro-Giene (+3 more)
CAS 7681-65-4
Copper(I) iodide (CAS 7681-65-4) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Copper(I) iodide is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H335, H372, H400).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
18
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Copper(I) iodide
CAS Number
7681-65-4
DTXSID
DTXSID5041803
Molecular Formula
Cu.HI
InChI Key
LSXDOTMGLUJQCM-UHFFFAOYSA-M
Monoisotopic Mass
190.841895
Synonyms
Cuprous iodideCopper iodide,Copper iodide (CuI)EINECS 231-674-6Hydro-GieneNatural marshiteEPA Pesticide Chemical Code 108301UNII-7DE9CA6IL2
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
BiocideDeodorizerStabilizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.07 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =1 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 7DE9CA6IL2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7DE9CA6IL2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7DE9CA6IL2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7DE9CA6IL2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =10 | mg/L | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/L | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =156 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =370 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| >1500 | ppm | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =0.2 | mg/m3 | LOEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| >=2 | mg/m3 | NOAEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =3 | mg/L | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =10 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =78 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =185 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =1000 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 18 of 18 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Copper iodide | 231-674-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
What regulatory lists include Copper(I) iodide?
Copper(I) iodide appears on 3 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, Europe; plastic_additive, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Copper(I) iodide used in cosmetics?
Yes, Copper(I) iodide is also indexed as a cosmetic ingredient under the name Cuprous Iodide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Copper(I) iodide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Copper(I) iodide have different safety status in cosmetics vs industrial chemicals?
Copper(I) iodide is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H335, H372, H400).
Is Copper(I) iodide used outside industrial chemicals?
Copper(I) iodide also appears in cosmetics databases.