Also known as: Caswell No. 776, Chlorox, Cloropool, Clorox liquid bleach, Deosan Green Label Steriliser (+14 more)
CAS 7681-52-9
Sodium hypochlorite (CAS 7681-52-9) is a chemical substance with GHS signal word Danger; key hazard signal: H314; H318; H400; H410. Key regulatory status: REACH registered, 42 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Sodium hypochlorite is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H318, H400, H410).
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Corr. 1B; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 | H314; H318; H400; H410 | GHS05; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | May be osive to metals Causes skin and eye irritation Very toxic to aquatic life |
| Short-term Effects | The substance is irritating to the eyes, skin, respiratory tract and digestive tract. See Notes. |
| Long-term Effects | Repeated or prolonged contact with skin may cause dermatitis. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| - | Journal of Chemical Engineering & Process Technology | Published Articles |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Cleaning products and household care; Europe | Danish EPA | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 240 | min | Breakthrough Time | Dermal | - | NTP_ICE_skin_irritation |
| =1.55 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| DY38VHM5OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DY38VHM5OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DY38VHM5OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DY38VHM5OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 130 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 200 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 250 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 346 | mg/kg bw/day | NOAEL | oral | guinea pig | COSMOS_DB |
| 393 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 5000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 5075 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =30 | mM | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 15 of 15 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium hypochlorite | 231-668-3 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Sodium hypochlorite (CAS 7681-52-9) is classified under EU CLP Annex VI as Skin Corr. 1B; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H314; H318; H400; H410. Source: EU CLP Annex VI (ECHA).
Sodium hypochlorite has 15 NOAEL studies in the database. The lowest reported value is 1.55 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Sodium hypochlorite appears on 10 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), active_ingredient; Pesticides, active_ingredient; Europe; Pesticides, and 7 more. Source: EPA CPDat.
Yes, Sodium hypochlorite is also indexed as a cosmetic ingredient under the name Sodium Hypochlorite. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Sodium hypochlorite is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H318, H400, H410).
Sodium hypochlorite also appears in cosmetics, pharmaceutical, cannabis databases.