What is the NOAEL for Camphor?
Camphor has 11 NOAEL studies in the database. The lowest reported value is 17.632 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Camphor
Also known as: dl-Camphor, Camphor - (C10H16O), 0-07-00-00135, 4-07-00-00213, Bornane, 2-oxo- (+15 more)
CAS 76-22-2
Camphor (CAS 76-22-2) is a chemical substance. Key regulatory status: REACH registered, 40 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
Camphor is classified GHS Danger (H228, H302, H315, H332, H371, H373) in the chemicals database but is restricted in EU cosmetics at max 11% in non-mucous-membrane products; prohibited in products for children under 3 years.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
40
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Camphor
CAS Number
76-22-2
DTXSID
DTXSID5030955
Molecular Formula
C10H16O
InChI Key
DSSYKIVIOFKYAU-UHFFFAOYSA-N
Monoisotopic Mass
152.120115
Synonyms
dl-CamphorCamphor - (C10H16O)0-07-00-001354-07-00-00213Bornane, 2-oxo-BRN 1907611BRN 3196099Camphor, syntheticCaswell No. 155EINECS 200-945-0EINECS 244-350-4EPA Pesticide Chemical Code 015602
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in convulsions and respiratory depression. Ingestion could cause death. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation and by ingestion. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
4 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 2 mg/m³ | - | 2 | N |
| NIOSH | TWA | 2 mg/m³ | - | 2 | N |
| CAL/OSHA | TWA | 2 mg/m³ | - | 2 | N |
| NIOSH | IDLH | 200 mg/m³ | - | 200 | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragrancePharmaceuticalPlasticizerDeodorizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
40 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| air; consumer_product; detected; emissions | Elsevier | CPCat |
| consumer_product; detected | Elsevier | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| air; detected; emissions; Personal care | Elsevier | CPCat |
| air; Cleaning products and household care; detected; emissions | Elsevier | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| detected; MN Chemical Screening; surface_water | USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | USGS | State of Minnesota |
| detected; ground_water; MN Chemical Screening | Minnesota Pollution Control Agency | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Pesticides | National Park Service | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =17.632 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 5TJD82A1ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5TJD82A1ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5TJD82A1ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5TJD82A1ET | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.5 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =400 | mg/kg bw/day | LEL | dermal | Mouse | ToxValDB_ECHA_IUCLID |
| =250 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| 800 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =1000 | mg/kg bw/day | NOAEL | dermal | Mouse | ToxValDB_ECHA_IUCLID |
| =6000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Bornan-2-one | 200-945-0 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
11% in non-mucous-membrane products; prohibited in products for children under 3 years
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
CAMPHOR
ChEMBL Phase
3
Adverse Events
24
Bioactivity
8
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Camphor?
Camphor appears on 25 regulatory/inventory lists including IFRA Transparency, active_ingredient; Europe; Pesticides, active_ingredient; Pesticides, and 22 more. Source: EPA CPDat.
What are the occupational exposure limits for Camphor?
Occupational exposure limits for Camphor are set by OSHA, NIOSH, CAL/OSHA. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Camphor used in cosmetics?
Yes, Camphor is also indexed as a cosmetic ingredient under the name Camphor. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Camphor come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Camphor have different safety status in cosmetics vs industrial chemicals?
Camphor is classified GHS Danger (H228, H302, H315, H332, H371, H373) in the chemicals database but is restricted in EU cosmetics at max 11% in non-mucous-membrane products; prohibited in products for children under 3 years.
Is Camphor used outside industrial chemicals?
Camphor also appears in cosmetics, pharmaceutical, cannabis databases.