NOAEL Data Cosmetic Ingredient

4-Methylpentane-2,3-dione

Also known as: Acetyl isobutyryl

CAS 7493-58-5

4-Methylpentane-2,3-dione (CAS 7493-58-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for 4-Methylpentane-2,3-Dione →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
4-Methylpentane-2,3-dione
CAS Number
7493-58-5
DTXSID
DTXSID90864077
Molecular Formula
C6H10O2
InChI Key
JENYBWHRLYZSSZ-UHFFFAOYSA-N
Monoisotopic Mass
114.06808
Synonyms
Acetyl isobutyryl

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
EuropeEuropean CommissionFl@vis

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
K372XXT72SUNIIFDA UNII substance identifier--openFDA substances
K372XXT72SUNIIFDA UNII substance identifier--openFDA substances
K372XXT72SUNIIFDA UNII substance identifier--openFDA substances
K372XXT72SUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 4-Methylpentane-2,3-dione?

4-Methylpentane-2,3-dione has 4 NOAEL studies in the database. The lowest reported value is K372XXT72S UNII. Source: openFDA substances.

What regulatory lists include 4-Methylpentane-2,3-dione?

4-Methylpentane-2,3-dione appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.

Is 4-Methylpentane-2,3-dione used in cosmetics?

Yes, 4-Methylpentane-2,3-dione is also indexed as a cosmetic ingredient under the name 4-Methylpentane-2,3-Dione. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 4-Methylpentane-2,3-dione come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 4-Methylpentane-2,3-dione used outside industrial chemicals?

4-Methylpentane-2,3-dione also appears in cosmetics databases.