What is the NOAEL for [2-(1-Propoxyethoxy)ethyl]benzene?
[2-(1-Propoxyethoxy)ethyl]benzene has 9 NOAEL studies in the database. The lowest reported value is U811MB854I UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
[2-(1-Propoxyethoxy)ethyl]benzene
Also known as: Acetal R, Acetaldehyde phenylethyl propyl acetal, Acetaldehyde propyl phenylethyl acetal, EINECS 231-327-9, FEMA No. 2004 (+4 more)
CAS 7493-57-4
[2-(1-Propoxyethoxy)ethyl]benzene (CAS 7493-57-4) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Acetaldehyde Phenethyl Propyl Acetal →
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
[2-(1-Propoxyethoxy)ethyl]benzene
CAS Number
7493-57-4
DTXSID
DTXSID2052493
Molecular Formula
C13H20O2
InChI Key
FMYCPRQGKSONCP-UHFFFAOYSA-N
Monoisotopic Mass
208.14633
Synonyms
Acetal RAcetaldehyde phenylethyl propyl acetalAcetaldehyde propyl phenylethyl acetalEINECS 231-327-9FEMA No. 2004Pepital1-Phenethoxy-1-propoxyethanePropyl phenethyl acetalUNII-U811MB854I
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
13 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| U811MB854I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U811MB854I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U811MB854I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| U811MB854I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 310 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3375 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | [2-(1-propoxyethoxy)ethyl]benzene | 231-327-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include [2-(1-Propoxyethoxy)ethyl]benzene?
[2-(1-Propoxyethoxy)ethyl]benzene appears on 4 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency, and 1 more. Source: EPA CPDat.
Is [2-(1-Propoxyethoxy)ethyl]benzene used in cosmetics?
Yes, [2-(1-Propoxyethoxy)ethyl]benzene is also indexed as a cosmetic ingredient under the name Acetaldehyde Phenethyl Propyl Acetal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for [2-(1-Propoxyethoxy)ethyl]benzene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is [2-(1-Propoxyethoxy)ethyl]benzene used outside industrial chemicals?
[2-(1-Propoxyethoxy)ethyl]benzene also appears in cosmetics, food safety, cannabis databases.