What is the NOAEL for 1-Butoxy-1-oxopropan-2-yl butanoate?
1-Butoxy-1-oxopropan-2-yl butanoate has 7 NOAEL studies in the database. The lowest reported value is OCR0ONT89C UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Butoxy-1-oxopropan-2-yl butanoate
Also known as: 1-(Butoxycarbonyl)-ethyl butyrate, Butanoic acid, 2-butoxy-1-methyl-2-oxoethyl ester, 3-03-00-00481, BRN 1709603, 2-Butoxy-1-methyl-2-oxoethyl butanoate (+7 more)
CAS 7492-70-8
1-Butoxy-1-oxopropan-2-yl butanoate (CAS 7492-70-8) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
1-Butoxy-1-oxopropan-2-yl butanoate
CAS Number
7492-70-8
DTXSID
DTXSID3044831
Molecular Formula
C11H20O4
InChI Key
NORZZKKLCYMBBF-UHFFFAOYSA-N
Monoisotopic Mass
216.136159
Synonyms
1-(Butoxycarbonyl)-ethyl butyrateButanoic acid, 2-butoxy-1-methyl-2-oxoethyl ester3-03-00-00481BRN 17096032-Butoxy-1-methyl-2-oxoethyl butanoateButyl butyrolactateButyl butyryl lactateEINECS 231-326-3FEMA No. 2190Lactic acid, butyl ester, butyrateNSC 166507UNII-OCR0ONT89C
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| OCR0ONT89C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCR0ONT89C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCR0ONT89C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCR0ONT89C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Butyl O-butyryllactate | 231-326-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1-Butoxy-1-oxopropan-2-yl butanoate?
1-Butoxy-1-oxopropan-2-yl butanoate appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is 1-Butoxy-1-oxopropan-2-yl butanoate used in cosmetics?
Yes, 1-Butoxy-1-oxopropan-2-yl butanoate is also indexed as a cosmetic ingredient under the name Butyl Butyrolactate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Butoxy-1-oxopropan-2-yl butanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-Butoxy-1-oxopropan-2-yl butanoate used outside industrial chemicals?
1-Butoxy-1-oxopropan-2-yl butanoate also appears in cosmetics, food safety, cannabis databases.