NOAEL Data Cosmetic Ingredient

1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone

Also known as: 1-​Propanone, 1-​(1,​2,​3,​4-​tetrahydro-​4,​4-​dimethyl-​1-​naphthalenyl)​-, 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphtyl)propan-1-one, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphtyl)propane-1-one, 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-on (+3 more)

CAS 74499-60-8

1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone (CAS 74499-60-8) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone
CAS Number
74499-60-8
DTXSID
DTXSID30868312
Molecular Formula
C15H20O
InChI Key
GNONYQJSCSRZOC-UHFFFAOYSA-N
Monoisotopic Mass
216.151415
Synonyms
1-​Propanone, 1-​(1,​2,​3,​4-​tetrahydro-​4,​4-​dimethyl-​1-​naphthalenyl)​-1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphtyl)propan-1-one1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphtyl)propane-1-one1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-on1-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthyl)propan-1-one1-Propionyl-4,4-dimethyl-1,2,3,4-tetrahydronaphthalene1-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)propan-1-one

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Fragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
IFRA TransparencyIFRAIFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
6ELC2PL542UNIIFDA UNII substance identifier--openFDA substances
6ELC2PL542UNIIFDA UNII substance identifier--openFDA substances
6ELC2PL542UNIIFDA UNII substance identifier--openFDA substances
6ELC2PL542UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone?

1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone has 4 NOAEL studies in the database. The lowest reported value is 6ELC2PL542 UNII. Source: openFDA substances.

What regulatory lists include 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone?

1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.

Is 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone used in cosmetics?

Yes, 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone is also indexed as a cosmetic ingredient under the name Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone used outside industrial chemicals?

1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthalenyl)-1-propanone also appears in cosmetics databases.