What is the GHS hazard classification for Zirconium?
Zirconium (CAS 7440-67-7) is classified under EU CLP Annex VI as Pyr. Sol. 1; Water-react. 1 with signal word Danger. Hazard statements: H250; H260. Source: EU CLP Annex VI (ECHA).
Danger
GHS02
NOAEL Data
REACH Registered
Cosmetic Ingredient
Zirconium
Also known as: EINECS 231-176-9, UNII-C6V6S92N3C, 40Zr, Zircat, Zirkonium (+4 more)
CAS 7440-67-7
Zirconium (CAS 7440-67-7) is a chemical substance with GHS signal word Danger; key hazard signal: H250; H260. Key regulatory status: REACH registered, 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
Zirconium is classified GHS Danger (H250, H260) in the chemicals database but is restricted in EU cosmetics at max II/391.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
15 fields
Name
Zirconium
CAS Number
7440-67-7
DTXSID
DTXSID0049818
Molecular Formula
Zr
InChI Key
QCWXUUIWCKQGHC-UHFFFAOYSA-N
Monoisotopic Mass
89.904698
Synonyms
EINECS 231-176-9UNII-C6V6S92N3C40ZrZircatZirkoniumZrzirconiozirconium(4+) ionzirconium atom
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Pyr. Sol. 1; Water-react. 1 | H250; H260 | GHS02 | Danger |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
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ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | May cause mechanical irritation to the eyes. |
| Long-term Effects | Repeated or prolonged inhalation of dust particles may cause effects on the lungs. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
8 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 5 mg/m³ | - | 5 | N |
| NIOSH | TWA | 5 mg/m³ | - | 5 | N |
| NIOSH | STEL | 10 mg/m³ | - | 10 | N |
| ACGIH | TWA | 5 mg/m³ [1992] | - | 5 | N |
| ACGIH | STEL | 10 mg/m³ [1992] | - | 10 | N |
| CAL/OSHA | TWA | 5 mg/m³ | - | 5 | N |
| CAL/OSHA | STEL | 10 mg/m³ | - | 10 | N |
| NIOSH | IDLH | 50 mg/m³ | - | 50 | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Antiperspirant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| detected; Europe; Personal care - make-up and related - eye liner | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
| banned; Europe; Personal care | European Commission | CosIng |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| C6V6S92N3C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C6V6S92N3C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C6V6S92N3C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| C6V6S92N3C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.79 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_PPRTV_(CPHEA) |
| =0.00008 | mg/kg bw/day | RfD (provisional) | oral | Human | ToxValDB_PPRTV_(CPHEA) |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Zirconium | 231-176-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
II/391
Category
Other
Frequently Asked Questions
What is the NOAEL for Zirconium?
Zirconium has 7 NOAEL studies in the database. The lowest reported value is 5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
What regulatory lists include Zirconium?
Zirconium appears on 6 regulatory/inventory lists including detected; Europe; Personal care - make-up and related - eye liner, Arts and crafts/Office supplies - body paint; detected; Europe, detected; Europe; Other direct contact consumer goods, and 3 more. Source: EPA CPDat.
What are the occupational exposure limits for Zirconium?
Occupational exposure limits for Zirconium are set by OSHA, NIOSH, ACGIH. 8 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Zirconium used in cosmetics?
Yes, Zirconium is also indexed as a cosmetic ingredient under the name ZIRCONIUM POWDER. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Zirconium come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Zirconium have different safety status in cosmetics vs industrial chemicals?
Zirconium is classified GHS Danger (H250, H260) in the chemicals database but is restricted in EU cosmetics at max II/391.
Is Zirconium used outside industrial chemicals?
Zirconium also appears in cosmetics databases.