What is the NOAEL for Tin?
Tin has 21 NOAEL studies in the database. The lowest reported value is 71 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Tin
Also known as: CI Pigment metal 5, EINECS 231-141-8, UNII-387GMG9FH5, Stannum metallicum
CAS 7440-31-5
Tin (CAS 7440-31-5) is a chemical substance. Key regulatory status: REACH registered, 30 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
Tin is prohibited in EU cosmetics but has active industrial GHS classifications (H319, H335, H372).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
21
SOURCE
chemical inventory jurisdictions
Regulatory lists
30
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Tin
CAS Number
7440-31-5
DTXSID
DTXSID1049801
Molecular Formula
Sn
InChI Key
ATJFFYVFTNAWJD-UHFFFAOYSA-N
Monoisotopic Mass
119.902202
Synonyms
CI Pigment metal 5EINECS 231-141-8UNII-387GMG9FH5Stannum metallicum
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | May cause mechanical irritation to the respiratory tract. |
| Long-term Effects | The substance may have effects on the lungs. This may result in a benign pneumoconiosis (stannosis). |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
4 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 2 mg/m³ | - | 2 | N |
| NIOSH | TWA | 2 mg/m³ | - | 2 | N |
| CAL/OSHA | TWA | 2 mg/m³ | - | 2 | N |
| NIOSH | IDLH | 100 mg/m³ | - | 100 | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
26 records
Surfactant (surface active agent)Stabilizing agentDegradant/impuritySurface modifierCorrosion inhibitorAntioxidantPlating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
30 records
| List | Keyword | Source |
|---|---|---|
| detected; Europe; Personal care - make-up and related - eye liner | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| Europe; nondetect; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Furniture and Furnishings | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Home maintenance - caulk/sealant | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Toys and children's products | Springer | Published Articles |
| Arts and crafts/Office supplies - children's art and toys - modeling clay; detected | Springer | Published Articles |
| nondetect; Other indirect contact consumer goods | Danish EPA | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 21 of 21 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =71 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 387GMG9FH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387GMG9FH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387GMG9FH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387GMG9FH5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =264 | mg/kg diet | LOAEL | oral | - | INCHEM_WHO_cicads_cicads_cicad65 |
| =264 | mg/kg diet | LOAEL | oral | - | INCHEM_WHO_cicads_cicads_cicad65 |
| =0.3 | mg/kg bw/day | MRL | oral | Human | ToxValDB_ATSDR_MRLs |
| =30 | mg/kg bw/day | NOAEL | oral | Rat | INCHEM_WHO_cicads_cicads_cicad65 |
| =30 | mg/kg bw | NOAEL | - | Rat | INCHEM_WHO_cicads_cicads_cicad65 |
| =30 | mg/kg bw/day | NOAEL | oral | Rat | INCHEM_WHO_cicads_cicads_cicad65 |
| =30 | mg/kg bw | NOAEL | - | Rat | INCHEM_WHO_cicads_cicads_cicad65 |
| =32 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ATSDR_MRLs |
| =32 | mg/kg/day | NOAEL | oral | Rat (Wistar; M/F) | ATSDR_toxval_ATSDR_MRLs.xlsx |
| =130 | mg/kg bw/day | NOAEL | oral | Mouse | INCHEM_WHO_cicads_cicads_cicad65 |
| =130 | mg/kg bw/day | NOAEL | oral | Mouse | INCHEM_WHO_cicads_cicads_cicad65 |
| =180 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_cicads_cicads_cicad65 |
| =180 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_cicads_cicads_cicad65 |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >1000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =0.6 | mg/kg bw/day | RfD | oral | Human | ToxValDB_RSL |
Showing 21 of 21 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tin | 231-141-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: 14 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Tin?
Tin appears on 14 regulatory/inventory lists including detected; Europe; Personal care - make-up and related - eye liner, Arts and crafts/Office supplies - body paint; detected; Europe, detected; Europe; Other direct contact consumer goods, and 11 more. Source: EPA CPDat.
What are the occupational exposure limits for Tin?
Occupational exposure limits for Tin are set by OSHA, NIOSH, CAL/OSHA. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Tin used in cosmetics?
Yes, Tin is also indexed as a cosmetic ingredient under the name Tin (Sn). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Tin have different safety status in cosmetics vs industrial chemicals?
Tin is prohibited in EU cosmetics but has active industrial GHS classifications (H319, H335, H372).
Is Tin used outside industrial chemicals?
Tin also appears in cosmetics, food safety, cannabis databases.