What is the NOAEL for Platinum?
Platinum has 8 NOAEL studies in the database. The lowest reported value is 49DFR088MY UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Platinum
Also known as: EINECS 231-116-1, UNII-49DFR088MY, Platinum metallicum, 78Pt, Platin (+5 more)
CAS 7440-06-4
Platinum (CAS 7440-06-4) is a chemical substance. Key regulatory status: REACH registered, 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
Platinum is classified GHS Danger (H228, H315, H319, H334, H335) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Platinum
CAS Number
7440-06-4
DTXSID
DTXSID9064681
Molecular Formula
Pt
InChI Key
BASFCYQUMIYNBI-UHFFFAOYSA-N
Monoisotopic Mass
194.964792
Synonyms
EINECS 231-116-1UNII-49DFR088MYPlatinum metallicum78PtPlatinPtPt(0)Ptnplatinum metalplatinum(0)
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Hazard Statements | No hazard classification according to GHS criteria |
| Short-term Effects | The substance is irritating to the eyes and respiratory tract. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
8 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| NIOSH | TWA | 1 mg/m³ | - | 1 | N |
| ACGIH | TWA | 1 mg/m³ [1979] | - | 1 | N |
| CAL/OSHA | TWA | 1 mg/m³ | - | 1 | N |
| OSHA | TWA | 0.002 mg/m³ | - | 0.002 | N |
| NIOSH | TWA | 0.002 mg/m³ | - | 0.002 | N |
| ACGIH | TWA | 0.002 mg/m³ [1979] | - | 0.002 | N |
| CAL/OSHA | TWA | 0.002 mg/m³ | - | 0.002 | N |
| NIOSH | IDLH | 4 mg/m³ | - | 4 | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
AbrasiveBiocideAntioxidantDeodorizerSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 49DFR088MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49DFR088MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49DFR088MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 49DFR088MY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| range:0.08-0.10.1 | mg/m3 | LOAEL | - | - | INCHEM_WHO_kemi_kemi_ah1997_14 |
| range:0.08-0.10.1 | mg/m3 | LOAEL | - | - | INCHEM_WHO_kemi_kemi_ah1997_14 |
| range:0.08-0.10.1 | mg/m3 | LOAEL | - | - | INCHEM_WHO_kemi_kemi_ah1997_14 |
| range:0.08-0.10.1 | mg/m3 | LOAEL | - | - | INCHEM_WHO_kemi_kemi_ah1997_14 |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Platinum | 231-116-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
SCCS Opinions
EU Scientific Committee opinions tied to the matched substance.
SOURCE
EU SCCS
1 opinions
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1630/21 | 24-25 June 2021 | insufficient data | Not determined | Limited/missing essential information; potential systemic uptake with organ accumulation (liver/spleen); potential mutagenic/genotoxic effects from literature; basis for concern over consumer risk |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
33
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Platinum?
Platinum appears on 3 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), Canada; pharmaceutical, Arts and crafts/Office supplies - body paint - tattoo ink; detected; Europe. Source: EPA CPDat.
What are the occupational exposure limits for Platinum?
Occupational exposure limits for Platinum are set by NIOSH, ACGIH, CAL/OSHA. 8 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Platinum used in cosmetics?
Yes, Platinum is also indexed as a cosmetic ingredient under the name Platinum. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Platinum come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Platinum have different safety status in cosmetics vs industrial chemicals?
Platinum is classified GHS Danger (H228, H315, H319, H334, H335) in the chemicals database but is restricted in EU cosmetics.
Is Platinum used outside industrial chemicals?
Platinum also appears in cosmetics, pharmaceutical databases.