What is the NOAEL for Potassium pyrophosphate?
Potassium pyrophosphate has 11 NOAEL studies in the database. The lowest reported value is 17.63 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Potassium pyrophosphate
Also known as: Potassium diphosphate (K4P2O7), Diphosphoric acid, tetrapotassium salt, UN 3287, Potassium phosphate (K4P2O7), EINECS 230-785-7 (+2 more)
CAS 7320-34-5
Potassium pyrophosphate (CAS 7320-34-5) is a chemical substance. Key regulatory status: REACH registered, 25 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
View cosmetic safety profile for Tetrapotassium Pyrophosphate →
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
25
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Potassium pyrophosphate
CAS Number
7320-34-5
DTXSID
DTXSID3036446
Molecular Formula
4K.H4O7P2
InChI Key
RYCLIXPGLDDLTM-UHFFFAOYSA-J
Monoisotopic Mass
333.798052
Synonyms
Potassium diphosphate (K4P2O7)Diphosphoric acid, tetrapotassium saltUN 3287Potassium phosphate (K4P2O7)EINECS 230-785-7Tetrapotassium diphosphorateUNII-B9W4019H5G
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of dust. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
38 records
Chelating agentpH regulating agentCorrosion inhibitorSurfactant (surface active agent)Oxidizing agentOtherThickening agentEmulsifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
25 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; Specialty occupational products | Danish Environmental Protection Agency | Danish EPA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =17.63 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| B9W4019H5G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B9W4019H5G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B9W4019H5G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B9W4019H5G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >1.1 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >7940 | mg/kg bw/day | LEL | dermal | Rabbit | ToxValDB_ECHA_IUCLID |
| =145.7 | mg/kg bw/day | NOAEL | oral | Human | ToxValDB_PPRTV_(CPHEA) |
| =1 | mg/kg bw/day | RfD | oral | Human | ToxValDB_RSL |
| =4 | mg/kg bw/day | RfD | oral | Human | ToxValDB_RSL |
| =49 | mg/kg bw/day | RfD (provisional) | oral | Human | ToxValDB_PPRTV_(CPHEA) |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tetrapotassium pyrophosphate | 230-785-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E450v — ADI: 40 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Potassium pyrophosphate?
Potassium pyrophosphate appears on 8 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), inert_ingredient; non_food_use; Pesticides, animal_products, and 5 more. Source: EPA CPDat.
Is Potassium pyrophosphate used in cosmetics?
Yes, Potassium pyrophosphate is also indexed as a cosmetic ingredient under the name Tetrapotassium Pyrophosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Potassium pyrophosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Potassium pyrophosphate used outside industrial chemicals?
Potassium pyrophosphate also appears in cosmetics, food safety, cannabis databases.